The heterocyclic compounds have a great importance in medicinal chemistry. One of the
most important heterocycles in medicinal chemistry are quinazolines possessing wide …

Creating effective, ecologically friendly, and commercially viable synthetic routes is crucial in
the design and synthesis of organic substances. Quinazoline, a heterocyclic compound with …

Urease is a kind of enzyme which could be found in various bacteria, fungi, plants, and
algae, which can quickly catalyze the hydrolysis of urea into ammonia and carbon dioxide …

A set of novel N-substituted-2-((4-oxo-3-phenyl-3, 4-dihydroquinazolin-2-yl) thio) acetamide
3–16 were designed and synthesized from 2-mercapto-3-phenylquinazolinone 2. The …

Abstract A new series of 1, 3, 5-triazine incorporating aromatic quinazolinone moieties as a
potential antimicrobial agents is reported. The first chlorine group of the cyanuric chloride (1) …

Sulfonamides are privileged candidates with potent anti-methicillin-resistant Staphylococcus
aureus (MRSA) activity and could replenish the MRSA antibiotic pipeline. The initial …

We report here a transition metal-free synthesis of quinazoline derivatives starting from 2-
aminobenzyl alcohols and aryl amides via an alcohol dehydrogenation strategy promoted …

A novel two series of S-alkylated quinazolinones 4–10 and N-alkylated quinazolinones 11–
17 was designed and synthesized as potential PARP-1 inhibitors. Quinazolinone scaffold …

A HPLC-UV guided fractionation of the culture broth of Streptomyces sp. CNQ-617 has led to
the isolation of a new quinazolinone derivative, actinoquinazolinone (1), as well as two …

We have carried out the synthesis of new 4-oxoquinazolin-3 (4H)-yl) furan-2-carboxamide
derivatives by the reaction between isatoic anhydride, 2-furoic hydrazide and substituted …