Polyphenols: A concise overview on the chemistry, occurrence, and human health

A Durazzo, M Lucarini, EB Souto, C Cicala… - Phytotherapy …, 2019 - Wiley Online Library
This review gives an updated picture of each class of phenolic compounds and their
properties. The most common classification implies the subdivision of phenolics in two main …

Natural compounds and combination therapy in colorectal cancer treatment

A Rejhová, A Opattová, A Čumová, D Slíva… - European journal of …, 2018 - Elsevier
Colorectal cancer (CRC) therapy using conventional chemotherapeutics represents a
considerable burden for the patient's organism because of high toxicity while the response is …

[HTML][HTML] Standardized extract of ginger ameliorates liver cancer by reducing proliferation and inducing apoptosis through inhibition oxidative stress/inflammation …

AA Hamza, GH Heeba, S Hamza, A Abdalla… - Biomedicine & …, 2021 - Elsevier
Ginger has been proposed as quite a promising candidate for cancer prevention. The
purpose of this study was to assess the chemo-preventive effects of ginger. Furthermore, this …

Molecular targets of natural compounds with anti-cancer properties

M Kubczak, A Szustka, M Rogalińska - International Journal of Molecular …, 2021 - mdpi.com
Cancer is the second leading cause of death in humans. Despite rapid developments in
diagnostic methods and therapies, metastasis and resistance to administrated drugs are the …

Combining crocin and sorafenib improves their tumor-inhibiting effects in a rat model of diethylnitrosamine-induced cirrhotic-hepatocellular carcinoma

B Awad, AA Hamza, A Al-Maktoum, S Al-Salam, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Liver cancer represents one of the most lethal forms of cancer, with
hepatocellular carcinoma (HCC) accounting for the majority of its incidences and deaths …

Safranal prevents liver cancer through inhibiting oxidative stress and alleviating inflammation

Y Abdalla, A Abdalla, AA Hamza, A Amin - Frontiers in Pharmacology, 2022 - frontiersin.org
Despite all efforts, an effective and safe treatment for liver cancer remains elusive. Natural
products and their derived biomolecules are potential resources to mine for novel anti …

Cancer chemoprevention by dietary phytochemicals: Epidemiological evidence

RB Ruiz, PS Hernández - Maturitas, 2016 - Elsevier
Background In recent years, natural compounds called “phytochemicals”, which are present
in fruits, vegetables, and plants, have received special attention due to their potential to …

Quercetin as an innovative therapeutic tool for cancer chemoprevention: Molecular mechanisms and implications in human health

RA Rather, M Bhagat - Cancer medicine, 2020 - Wiley Online Library
Cancer is a life‐threatening disease afflicting human health worldwide. Recent advances in
drug discovery infrastructure and molecular approaches have helped a lot in identifying the …

Polyphenolic phytochemicals in cancer prevention and therapy: bioavailability versus bioefficacy

JM Estrela, S Mena, E Obrador… - Journal of medicinal …, 2017 - ACS Publications
Natural polyphenols are organic chemicals which contain phenol units in their structures.
They show antitumor properties. However, a key problem is their short half-life and low …

Polyphenols: dietary assessment and role in the prevention of cancers

JA Rothwell, V Knaze… - Current Opinion in Clinical …, 2017 - journals.lww.com
Polyphenol intake may mitigate cancer risk but this depends on cancer site, the subgroup of
compounds under study, and accurate assessment of dietary exposure. Further work must …