Time-lapse monitoring as a tool for clinical embryo assessment

K Kirkegaard, IE Agerholm, HJ Ingerslev - Human reproduction, 2012 - academic.oup.com
As elective transfer of a single embryo (eSET) becomes increasingly accepted, the need to
improve implantation rates becomes crucial. Selecting the most competent embryo therefore …

Oocyte and embryo quality: effect of origin, culture conditions and gene expression patterns

P Lonergan, D Rizos, A Gutierrez‐Adan… - … in Domestic Animals, 2003 - Wiley Online Library
Contents In general, the majority of immature bovine oocytes fail to develop to the blastocyst
stage following maturation, fertilization and culture in vitro. The evidence suggests that while …

Maternal diet and other factors affecting offspring sex ratio: a review

CS Rosenfeld, RM Roberts - Biology of reproduction, 2004 - academic.oup.com
Mammals usually produce approximately equal numbers of sons and daughters, but there
are exceptions to this general rule, as has been observed in ruminant ungulate species …

Sexual dimorphism in the formation, function and adaptation of the placenta

JI Kalisch-Smith, DG Simmons, H Dickinson, KM Moritz - Placenta, 2017 - Elsevier
Exposure of the embryo or fetus to perturbations in utero can result in intrauterine growth
restriction, a primary risk factor for the development of adult disease. However, despite …

Delayed and incomplete reprogramming of chromosome methylation patterns in bovine cloned embryos

D Bourc'his, D Le Bourhis, D Patin, A Niveleau… - Current Biology, 2001 - cell.com
Full-term development has now been achieved in several mammalian species by transfer of
somatic nuclei into enucleated oocytes [1, 2]. Although a high proportion of such …

[HTML][HTML] Effect of oxygen concentration on human embryo development evaluated by time-lapse monitoring

K Kirkegaard, JJ Hindkjaer, HJ Ingerslev - Fertility and sterility, 2013 - Elsevier
OBJECTIVE: To evaluate, using time-lapse monitoring, the temporal influence of culture in
5% O2 or 20% O2 on human embryonic development. DESIGN: Retrospective cohort study …

Sexual dimorphism among bovine embryos in their ability to make the transition to expanded blastocyst and in the expression of the signaling molecule IFN-τ

MA Larson, K Kimura, HM Kubisch… - Proceedings of the …, 2001 - National Acad Sciences
IFN-τ is a secretory product of trophectoderm of cattle, sheep, and their relatives and is
expressed for a few days in early pregnancy after the blastocyst first forms. It serves to alert …

A randomized clinical trial comparing embryo culture in a conventional incubator with a time-lapse incubator

K Kirkegaard, JJ Hindkjaer, ML Grøndahl… - Journal of Assisted …, 2012 - Springer
Purpose Time-lapse monitoring allows for a flexible embryo evaluation and potentially
provides new dynamic markers of embryo competence. Before introducing time-lapse …

[PDF][PDF] Effect of inhibitors and uncouplers of oxidative phosphorylation during compaction and blastulation of bovine embryos cultured in vitro

JG Thompson, C McNaughton… - … of reproduction and …, 2000 - researchgate.net
As with most cells, bovine pre-elongation embryos are highly dependent on oxidative
phosphorylation as the primary energy production pathway (that is, ATP generating …

Sire modulates developmental kinetics and transcriptome of the bovine embryo

KN Lockhart, JN Drum, AZ Balboula… - …, 2023 - rep.bioscientifica.com
In brief The first week of gestation is a period of major pregnancy loss in cattle, this study
reveals that the male plays a key role in regulating embryonic development during this time …