Background Currently, balanced diet and healthy foods are attracting increasing attention
due to their great health-beneficial effects. The tuber of Dioscorea (yam) is both edible and …

Plants including Rhizoma polgonati, Smilax china, and Trigonella foenum-graecum contain
a lot of diosgenin, a steroidal sapogenin. This bioactive phytochemical has shown high …

Plants and microbes interact with each other via different chemical signaling pathways. At
the risophere level, the microbes can secrete molecules, called elicitors, which act on their …

Background Chronic diseases are a major cause of mortality worldwide, and despite the
recent development in treatment modalities, synthetic drugs have continued to show toxic …

Diosgenin, a steroidal sapogenin, obtained from Trigonella foenum-graecum, Dioscorea,
and Rhizoma polgonati, has shown high potential and interest in the treatment of various …

Background Diabetic nephropathy (DN) is a serious complication of diabetes mellitus. DN is
the main cause of end-stage renal disease (ESRD). SIRT6 becomes the important target of …

Anthracyclines (ANTs) continue to play an irreplaceable role in oncology treatment.
However, the clinical application of ANTs has been limited. In the first place, ANTs can …

To endure respective research for cancer via common food ingredients has become more
prominent with preferably minuscule toxicity. Spices are emerging as a new source of …

Diosgenin (DSG) has attracted attention recently as a potential anticancer therapeutic agent
due to its profound antitumor activity. To better utilize DSG as an antitumor compound, two …

The role of estrogens in prostate cancer (PCa) is shrouded in mystery, with its actions going
from angelic to devilish. The findings by Huggins and Hodges establishing PCa as a …