How living cells deal with head‐on collisions of the replication and transcription complexes
has been debated for a long time. Even in the widely studied model bacteria Escherichia …

Friedreich's ataxia (FRDA) is caused by expansions of GAA• TTC repeats in the first intron of
the human FXN gene that occur during both intergenerational transmissions and in somatic …

The mechanism of mitochondrial DNA replication is a subject of intense debate. One model
proposes a strand-asynchronous replication in which both strands of the circular genome …

In the yeast S. cerevisiae, ARS (autonomously replicating sequence) elements located in the
intergenic spacers of the rRNA gene locus are infrequently activated as origins of …

To study the structure of partially replicated plasmids, we cloned the Escherichia coli polar
replication terminator TerE in its active orientation at different locations in the ColE1 vector …

The topology of plasmid DNA changes continuously as replication progresses. But the
dynamics of the process remains to be fully understood. Knotted bubbles form when topo IV …

Two-dimensional (2D) agarose gel electrophoresis is one of the most powerful methods to
analyze the mass and shape of replication intermediates. It is often use to map replication …

A series of plasmids were constructed containing two unidirectional ColE1 replication
origins in either the same or opposite orientations and their replication mode was …

Abstract Two-dimensional (2D) agarose gel electrophoresis was used to study termination of
DNA replication in a shuttle vector, YRp7′, when it replicated in Escherichia coli …

Bacteriophage λ genome is one of the classical model replicons in studies on the regulation
of DNA replication. Moreover, since genes coding for Shiga toxins are located in genomes of …