Innate immune receptors have a key role in immune surveillance by sensing
microorganisms and initiating protective immune responses. However, the innate immune …

Background Plasmodium vivax is one of the major species of malaria infecting humans.
Although emphasis on P. falciparum is appropriate, the burden of vivax malaria should be …

Cerebral malaria is a deadly outcome of infection by Plasmodium falciparum, occurring
when parasite-infected erythrocytes accumulate in the brain. These erythrocytes display …

Despite decades of research on cerebral malaria (CM) there is still a paucity of knowledge
about what actual causes CM and why certain people develop it. Although sequestration of …

Lactic acidosis and hyperlactatemia are common metabolic disturbances in patients with
severe malaria. Lactic acidosis causes physiological adverse effects, which can aggravate …

Sequestration of Plasmodium falciparum‐infected erythrocytes (IE) within the brain
microvasculature is a hallmark of cerebral malaria (CM). Using a microchannel flow …

The pathogenesis of infectious diseases depends on the interaction of host and pathogen. In
Plasmodium falciparum malaria, host and parasite processes can be assessed by dual RNA …

Visceral leishmaniasis is hypoendemic in Mediterranean countries, where it is caused by the
flagellate protozoan Leishmania infantum. VL cases in this area account for 5%–6% of the …

Plasmodium falciparum malaria and non-typhoid Salmonella (NTS) bacteraemia are both
major causes of morbidity and mortality in children in sub-Saharan Africa. Co-infections are …

The murine model of experimental cerebral malaria (ECM) has been utilised extensively in
recent years to study the pathogenesis of human cerebral malaria (HCM). However, it has …