Ambient air pollution increases the risk of cerebrovascular and neuropsychiatric disorders through induction of inflammation and oxidative stress

O Hahad, J Lelieveld, F Birklein, K Lieb… - International journal of …, 2020 - mdpi.com
Exposure to ambient air pollution is a well-established determinant of health and disease.
The Lancet Commission on pollution and health concludes that air pollution is the leading …

Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders

LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …

Association between ambient air pollution and amyloid positron emission tomography positivity in older adults with cognitive impairment

L Iaccarino, R La Joie, OH Lesman-Segev… - JAMA …, 2021 - jamanetwork.com
Importance Amyloid-β (Aβ) deposition is a feature of Alzheimer disease (AD) and may be
promoted by exogenous factors, such as ambient air quality. Objective To examine the …

Effects of air pollution particles (ultrafine and fine particulate matter) on mitochondrial function and oxidative stress–Implications for cardiovascular and …

A Daiber, M Kuntic, O Hahad, LG Delogu… - Archives of biochemistry …, 2020 - Elsevier
Environmental pollution is a major cause of global mortality and burden of disease. All
chemical pollution forms together may be responsible for up to 12 million annual excess …

[HTML][HTML] Associations between air pollution and biomarkers of Alzheimer's disease in cognitively unimpaired individuals

S Alemany, M Crous-Bou, N Vilor-Tejedor… - Environment …, 2021 - Elsevier
Background Air quality contributes to incidence of Alzheimer's disease (AD) although the
underlying neurobiological mechanisms are unclear. This study was aimed to examine the …

Air quality improvement and cognitive decline in community-dwelling older women in the United States: A longitudinal cohort study

D Younan, X Wang, J Millstein, AJ Petkus… - PLoS …, 2022 - journals.plos.org
Background Late-life exposure to ambient air pollution is a modifiable risk factor for
dementia, but epidemiological studies have shown inconsistent evidence for cognitive …

Neurovascular alterations in vascular dementia: emphasis on risk factors

S Lecordier, D Manrique-Castano… - Frontiers in aging …, 2021 - frontiersin.org
Vascular dementia (VaD) constitutes the second most prevalent cause of dementia in the
world after Alzheimer's disease (AD). VaD regroups heterogeneous neurological conditions …

Three month inhalation exposure to low-level PM2.5 induced brain toxicity in an Alzheimer's disease mouse model

SH Lee, YH Chen, CC Chien, YH Yan, HC Chen… - PLoS …, 2021 - journals.plos.org
Although numerous epidemiological studies revealed an association between ambient fine
particulate matter (PM2. 5) exposure and Alzheimer's disease (AD), the PM2. 5-induced …

Particulate matter and Alzheimer's disease: an intimate connection

DR O'Piela, GR Durisek, YNH Escobar… - Trends in molecular …, 2022 - cell.com
The environmental role in disease progression has been appreciated for decades; however,
understanding how airborne toxicant exposure can affect organs beyond the lungs is an …

Microglial Activation and Oxidative Stress in PM2.5-Induced Neurodegenerative Disorders

J Song, K Han, Y Wang, R Qu, Y Liu, S Wang, Y Wang… - Antioxidants, 2022 - mdpi.com
Fine particulate matter (PM2. 5) pollution remains a prominent environmental problem
worldwide, posing great threats to human health. The adverse effects of PM2. 5 on the …