In the last decade, biological drugs have rapidly proliferated and have now become an
important therapeutic modality. This is because of their high potency, high specificity and …

Alzheimer's disease (AD) and diabetes are currently considered among the top threats to
human health worldwide. Intriguingly, a connection between these diseases has been …

This position paper discusses progress made and to be made with so-called advanced drug
delivery systems, particularly but not exclusively those in the nanometre domain. The paper …

The formation of insulin amyloid can dramatically impact glycemic control in patients with
diabetes, making it an important therapeutic consideration. In addition, the cost associated …

Biologic therapeutics such as protein/polypeptide drugs are conventionally administered
systemically via intravenous injection for the treatment of diseases including lung diseases …

Obesity, metabolic syndrome, and asthma are all rapidly increasing globally. Substantial
emerging evidence suggests that these three conditions are epidemiologically and …

Alzheimer's disease is a devastating disorder that is estimated to affect more than 25 million
people worldwide and for which there are no preventive, disease-modifying, or curative …

Protein and peptide drugs administered subcutaneously, such as insulin can be
amyloidogenic and result in localized amyloid deposits at the sites of medication injections …

Lysozyme is associated with hereditary systemic amyloidosis in humans. Hen egg white
lysozyme (HEWL) has been extensively studied as an amyloid forming protein. In this study …

The current review was designed to compare between the insulin inhalation systems
Exubera and Afrezza and to investigate the reasons why Exubera was unsuccessful, when …