Soft biological materials and their impact on cell function

I Levental, PC Georges, PA Janmey - Soft Matter, 2007 - pubs.rsc.org
Most organs and biological tissues are soft viscoelastic materials with elastic moduli ranging
from on the order of 100 Pa for the brain to 100 000 Pa for soft cartilage. Biocompatible …

The role of ambulatory mechanics in the initiation and progression of knee osteoarthritis

TP Andriacchi, A Mündermann - Current opinion in rheumatology, 2006 - journals.lww.com
The initiation of osteoarthritis occurs when healthy cartilage experiences some condition
(traumatic or chronic) that causes kinematic changes during ambulation at the knee to shift …

Gait mechanics influence healthy cartilage morphology and osteoarthritis of the knee

TP Andriacchi, S Koo, SF Scanlan - JBJS, 2009 - journals.lww.com
The response of healthy and diseased cartilage of the knee to the mechanics of walking is
examined, with the goal of providing insight into the relationship between the kinematics and …

Etiology and pathogenesis of osteochondrosis

B Ytrehus, CS Carlson, S Ekman - Veterinary pathology, 2007 - journals.sagepub.com
Osteochondrosis is a common and clinically important joint disorder that occurs in human
beings and in multiple animal species, most commonly pigs, horses, and dogs. This disorder …

Autophagy and cartilage homeostasis mechanisms in joint health, aging and OA

MK Lotz, B Carames - Nature Reviews Rheumatology, 2011 - nature.com
Osteoarthritis (OA) is the most prevalent joint disease, but neither preventive measures nor
disease-modifying drugs are available and a continuing need exists for safe and effective …

[图书][B] Biomechanics of musculoskeletal injury

WC Whiting, RF Zernicke - 2008 - books.google.com
Biomechanics of Musculoskeletal Injury, Second Edition, presents clear, accessible
explanations of the biomechanical principles of injury and how injuries affect the normal …

[HTML][HTML] Individuals with patellofemoral pain exhibit greater patellofemoral joint stress: a finite element analysis study

S Farrokhi, JH Keyak, CM Powers - Osteoarthritis and Cartilage, 2011 - Elsevier
OBJECTIVE: To test the hypothesis that individuals with patellofemoral pain (PFP) exhibit
greater patellofemoral joint stress profiles compared to persons who are pain-free …

Chondrogenic progenitor cells respond to cartilage injury

D Seol, DJ McCabe, H Choe, H Zheng… - Arthritis & …, 2012 - Wiley Online Library
Objective Hypocellularity resulting from chondrocyte death in the aftermath of mechanical
injury is thought to contribute to posttraumatic osteoarthritis. However, we observed that …

In vivo articular cartilage deformation: noninvasive quantification of intratissue strain during joint contact in the human knee

DD Chan, L Cai, KD Butz, SB Trippel, EA Nauman… - Scientific reports, 2016 - nature.com
The in vivo measurement of articular cartilage deformation is essential to understand how
mechanical forces distribute throughout the healthy tissue and change over time in the …

Exercise and osteoarthritis

DJ Hunter, F Eckstein - Journal of anatomy, 2009 - Wiley Online Library
Exercise remains an extremely popular leisure time activity in many countries throughout the
western world. It is widely promoted in the lay press as having salutory benefits for weight …