New technological platforms, such as mRNA and adenoviral vector vaccines, have been utilized to develop coronavirus disease 2019 (COVID-19) vaccines. These new modalities …
The development of safe and effective second-generation COVID-19 vaccines to improve affordability and storage stability requirements remains a high priority to expand global …
CA Devaux, P Pontarotti, A Levasseur… - Frontiers in Public …, 2024 - frontiersin.org
The polioviruses (PVs) are mainly transmitted by direct contact with an infected person through the fecal-oral route and respiratory secretions (or more rarely via contaminated …
T Zhao, J Li, T Huang, ZF Ying, YC Che, ZM Zhao… - npj Vaccines, 2024 - nature.com
Trivalent oral poliovirus vaccine (tOPV) has been withdrawn and instead an inactivated poliovirus vaccine (IPV) and bivalent type 1 and type 3 OPV (bOPV) sequential …
M Aribi - New Topics in Vaccine Development, 2024 - books.google.com
Vaccinology, the scientific discipline focused on vaccines, has evolved from com-bating infectious diseases to addressing a wide array of a broad spectrum of health concerns …
P Kumar, M Wang, OS Kumru, JM Hickey… - … Therapy-Methods & …, 2023 - cell.com
Recombinant adeno-associated viruses (rAAVs) are a preferred vector system in clinical gene transfer. A fundamental challenge to formulate and deliver rAAVs as stable and …
P Kumar, DA Holland, K Secrist, P Taskar, B Dotson… - Vaccines, 2024 - mdpi.com
Introducing new recombinant protein antigens to existing pediatric combination vaccines is important in improving coverage and affordability, especially in low-and middle-income …
P Kumar, A Hamana, C Bird, B Dotson… - Vaccines, 2024 - mdpi.com
In this work, we describe compatibility assessments of a recombinant, trivalent non- replicating rotavirus vaccine (t-NRRV) candidate with a mock trivalent Sabin inactivated …
JM Hickey, OS Kumru, F Dalençon, F Arvis… - Journal of …, 2025 - jpharmsci.org
By evaluating the stability profiles of each component of a vaccine candidate (antigens, adjuvants), formulation conditions to mitigate vaccine instability can be identified. In this …