Glioblastoma progression in its early stages remains poorly understood. Here, we transfer
PDGFB and genetic barcodes in mouse brain to initiate gliomagenesis and enable direct …

Despite significant advancements in prevention and treatment, colorectal cancer (CRC)
remains the third leading cause of cancer-related deaths. Animal models have emerged as …

An ischemic stroke occurs when the blood supply is obstructed to the vascular basin,
causing the death of nerve cells and forming the ischemic core. Subsequently, the brain …

Simple Summary Glioblastoma is a rapidly progressing brain cancer that is very difficult to
treat. Given that many aspects of cell and tissue behavior are controlled by electric signaling …

Glioblastoma is a lethal primary brain tumor lacking effective therapy. The secluded onset
site, combined with the infiltrative properties of this tumor, require novel targeted therapies …

Cutaneous melanoma is an aggressive malignancy with high heterogeneity. Several studies
have been performed to identify cutaneous melanoma subtypes based on genomic profiling …

Simple Summary Brain tumor-initiating cells (BTICs) drive tumor progression and resistance
to treatments, posing formidable challenges to advancing effective treatments against …

Simple Summary Notch signaling plays a context-dependent role in multiple cancer types by
either promoting or suppressing tumor development. The role of the Notch receptors in the …

Uvod: Proces karcinogeneze može se javiti u svakoj ćeliji, tkivu ili organu što posledično
uzrokuje niz patoloških promena koje rezultuju nastankom velikog broja karcinoma …

Brain tumor-initiating cells (BTICs) drive tumor progression, immunosuppression, and
resistance to treatments, posing formidable challenges to advancing effective treatments …