Extracellular matrix-based materials for regenerative medicine

GS Hussey, JL Dziki, SF Badylak - Nature Reviews Materials, 2018 - nature.com
In tissue engineering and regenerative medicine, a biomaterial provides mechanical support
and biochemical signals to encourage cell attachment and modulate cell behaviour …

[HTML][HTML] Promoting tissue regeneration by modulating the immune system

Z Julier, AJ Park, PS Briquez, MM Martino - Acta biomaterialia, 2017 - Elsevier
The immune system plays a central role in tissue repair and regeneration. Indeed, the
immune response to tissue injury is crucial in determining the speed and the outcome of the …

Collagen—emerging collagen based therapies hit the patient

EA Abou Neel, L Bozec, JC Knowles, O Syed… - Advanced drug delivery …, 2013 - Elsevier
The choice of biomaterials available for regenerative medicine continues to grow rapidly,
with new materials often claiming advantages over the short-comings of those already in …

Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion

J Ma, H Zhan, W Li, L Zhang, F Yun, R Wu, J Lin… - Biomaterials …, 2021 - Springer
Intrauterine adhesion (IUA) is a common gynaecological disease that develops from
infection or trauma. IUA disease may seriously affect the physical and mental health of …

Extracellular matrix as an inductive scaffold for functional tissue reconstruction

BN Brown, SF Badylak - Translational Research, 2014 - Elsevier
The extracellular matrix (ECM) is a meshwork of both structural and functional proteins
assembled in unique tissue-specific architectures. The ECM both provides the mechanical …

A hydrogel derived from decellularized dermal extracellular matrix

MT Wolf, KA Daly, EP Brennan-Pierce, SA Johnson… - Biomaterials, 2012 - Elsevier
The ECM of mammalian tissues has been used as a scaffold to facilitate the repair and
reconstruction of numerous tissues. Such scaffolds are prepared in many forms including …

Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering

CW Cheng, LD Solorio, E Alsberg - Biotechnology advances, 2014 - Elsevier
The reconstruction of musculoskeletal defects is a constant challenge for orthopaedic
surgeons. Musculoskeletal injuries such as fractures, chondral lesions, infections and tumor …

Extracellular matrix-based biomaterials and their influence upon cell behavior

MC Cramer, SF Badylak - Annals of biomedical engineering, 2020 - Springer
Biologic scaffold materials composed of allogeneic or xenogeneic extracellular matrix (ECM)
are commonly used for the repair and remodeling of injured tissue. The clinical outcomes …

Decellularized allogeneic and xenogeneic tissue as a bioscaffold for regenerative medicine: factors that influence the host response

SF Badylak - Annals of biomedical engineering, 2014 - Springer
Biologic scaffold materials composed of mammalian extracellular matrix (ECM) are prepared
by decellularization of source tissues harvested from either humans (allogeneic) or a variety …

[HTML][HTML] RETRACTED: engineered whole organs and complex tissues

SF Badylak, DJ Weiss, A Caplan, P Macchiarini - The Lancet, 2012 - thelancet.com
End-stage organ failure is a key challenge for the medical community because of the ageing
population and the severe shortage of suitable donor organs available. Equally, injuries to …