Decoding type I and III interferon signalling during viral infection
EV Mesev, RA LeDesma, A Ploss - Nature microbiology, 2019 - nature.com
Interferon (IFN)-mediated antiviral responses are central to host defence against viral
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …
infection. Despite the existence of at least 20 IFNs, there are only three known cell surface …
Type A viral hepatitis: A summary and update on the molecular virology, epidemiology, pathogenesis and prevention
SM Lemon, JJ Ott, P Van Damme, D Shouval - Journal of Hepatology, 2018 - Elsevier
Although epidemic jaundice was well known to physicians of antiquity, it is only in recent
years that medical science has begun to unravel the origins of hepatitis A virus (HAV) and …
years that medical science has begun to unravel the origins of hepatitis A virus (HAV) and …
Toll-like receptors in antiviral innate immunity
SN Lester, K Li - Journal of molecular biology, 2014 - Elsevier
Toll-like receptors (TLRs) are fundamental sensor molecules of the host innate immune
system, which detect conserved molecular signatures of a wide range of microbial …
system, which detect conserved molecular signatures of a wide range of microbial …
Detection of microbial infections through innate immune sensing of nucleic acids
Microbial infections are recognized by the innate immune system through germline-encoded
pattern recognition receptors (PRRs). As most microbial pathogens contain DNA and/or …
pattern recognition receptors (PRRs). As most microbial pathogens contain DNA and/or …
Immune responses and immunopathology in acute and chronic viral hepatitis
Hepatitis A virus (HAV), hepatitis B virus (HBV) and hepatitis C virus (HCV) are responsible
for most cases of viral hepatitis. Infection by each type of virus results in a different typical …
for most cases of viral hepatitis. Infection by each type of virus results in a different typical …
[PDF][PDF] WHO immunological basis for immunization series: module 18: hepatitis A
World Health Organization - 2019 - apps.who.int
MAVS Mitochondrial antiviral signaling protein MMR Measles, mumps and rubella vaccine
MSM Men who have sex with men LAK Lymphokine-activated killer cells NK cells Natural …
MSM Men who have sex with men LAK Lymphokine-activated killer cells NK cells Natural …
Living in the liver: hepatic infections
The liver has vital metabolic and clearance functions that involve the uptake of nutrients,
waste products and pathogens from the blood. In addition, its unique immunoregulatory …
waste products and pathogens from the blood. In addition, its unique immunoregulatory …
Hepatitis A virus infection
Hepatitis A is a vaccine-preventable infection caused by the hepatitis A virus (HAV). Over
150 million new infections of hepatitis A occur annually. HAV causes an acute inflammatory …
150 million new infections of hepatitis A occur annually. HAV causes an acute inflammatory …
TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target
Abstract Toll/IL-1R domain-containing adaptor-inducing IFN-β (TRIF)-dependent signaling is
required for TLR-mediated production of type-I IFN and several other proinflammatory …
required for TLR-mediated production of type-I IFN and several other proinflammatory …
[PDF][PDF] Immune tolerance in liver disease
IN Crispe - Hepatology, 2014 - Wiley Online Library
Liver tolerance is manifest as a bias toward immune unresponsiveness, both in the context
of a major histocompatibility complex–mismatched liver transplant and in the context of liver …
of a major histocompatibility complex–mismatched liver transplant and in the context of liver …