Transforming growth factor β (TGF-β) has long been identified with its intensive involvement
in early embryonic development and organogenesis, immune supervision, tissue repair, and …

Transforming growth factor β (TGF-β) is a secreted cytokine that regulates cell proliferation,
migration, and the differentiation of a plethora of different cell types. Consistent with these …

Epithelial–mesenchymal transition (EMT) is a multistep process that allows epithelial cells to
acquire mesenchymal properties. Fundamental in the early stages of embryonic …

Mechanistic studies in DNA repair have focused on roles of multi-protein DNA complexes,
so how long non-coding RNAs (lncRNAs) regulate DNA repair is less well understood. Yet …

Lung cancer is one of the most malignant cancers around the world, with high morbidity and
mortality. Metastasis is the leading cause of lung cancer deaths and treatment failure …

Dysregulated gene expression and imbalance of transcriptional regulation are typical
features of cancer. RNA always plays a key role in these processes. Human transcripts …

Cancer is driven by genetic mutations in oncogenes and tumor suppressor genes and by
cellular events that develop a misregulated molecular microenvironment in the growing …

Transforming growth factor-β (TGF-β) is a crucial pathogenic mediator of inflammatory
diseases. In tissue fibrosis, TGF-β regulates the pathogenic activity of infiltrated …

Abstract Epithelial-mesenchymal transition (EMT), transforming growth factor β (TGF-β) and
reactive oxygen species (ROS) plays a central role in cancer metastasis. Moreover …

Long noncoding RNAs (lncRNAs) can act as oncogene and tumor suppressor genes in
many types of cancers including breast cancer (BC). Our previous study has indicated …