The Gram-negative bacterial lipopolysaccharide (LPS) is a major component of the outer membrane that plays a key role in host–pathogen interactions with the innate immune …
N Castro-Bravo, JM Wells, A Margolles… - Frontiers in …, 2018 - frontiersin.org
Exopolysaccharides (EPS) are surface carbohydrate polymers present in most bacteria acting as a protective surface layer but also interacting with the surrounding environment …
Helicobacter pylori is the first formally recognized bacterial carcinogen and is one of the most successful human pathogens, as over half of the world's population is colonized with …
C-type lectin receptors (CLRs) expressed by dendritic cells are crucial for tailoring immune responses to pathogens. Following pathogen binding, CLRs trigger distinct signalling …
How can probiotic bacteria transduce their health benefits to the host? Bacterial cell surface macromolecules are key factors in this beneficial microorganism–host crosstalk, as they can …
B Pulendran, D Artis - Science, 2012 - science.org
Nearly half of the world's population harbors helminth infections or suffers from allergic disorders. A common feature of this population is the so-called “type 2 immune response,” …
Multicellular organisms possess very sophisticated defense mechanisms that are designed to effectively counter the continual microbial insult of the environment within the vertebrate …
Pathogen recognition by C-type lectin receptors (CLRs) expressed by dendritic cells is important not only for antigen presentation, but also for the induction of appropriate adaptive …
Pattern-recognition receptors (PRRs) detect molecular signatures of microbes and initiate immune responses to infection. Prototypical PRRs such as Toll-like receptors (TLRs) signal …