CLIC and membrane wound repair pathways enable pandemic norovirus entry and infection
Globally, most cases of gastroenteritis are caused by pandemic GII. 4 human norovirus
(HuNoV) strains with no approved therapies or vaccines available. The cellular pathways …
(HuNoV) strains with no approved therapies or vaccines available. The cellular pathways …
Ceramide‐mediated orchestration of oxidative stress response through filopodia‐derived small extracellular vesicles
Extracellular vesicles (EVs) are shed from the plasma membrane, but the regulation and
function of these EVs remain unclear. We found that oxidative stress induced by H2O2 in …
function of these EVs remain unclear. We found that oxidative stress induced by H2O2 in …
Stress‐induced vesicular assemblies of dual leucine zipper kinase are signaling hubs involved in kinase activation and neurodegeneration
E Tortosa, A Sengupta Ghosh, Q Li, WR Wong… - The EMBO …, 2022 - embopress.org
Mitogen‐activated protein kinases (MAPKs) drive key signaling cascades during neuronal
survival and degeneration. The localization of kinases to specific subcellular compartments …
survival and degeneration. The localization of kinases to specific subcellular compartments …
Palmitoylation of acetylated tubulin and association with ceramide-rich platforms is critical for ciliogenesis
Microtubules are polymers composed of αβ-tubulin subunits that provide structure to cells
and play a crucial role in in the development and function of neuronal processes and cilia …
and play a crucial role in in the development and function of neuronal processes and cilia …
Evaluation of the relationship between intravascular hemolysis and clinical manifestations in sickle cell disease: decreased hemopexin during vaso-occlusive crises …
N Yildirim, S Unal, A Yalcinkaya, F Karahan… - Annals of Hematology, 2022 - Springer
The aims of this study were to determine the possible relationships between the levels of
hemin, hemopexin, acid sphingomyelinase, nitrite/nitrate (NOx), and other parameters in …
hemin, hemopexin, acid sphingomyelinase, nitrite/nitrate (NOx), and other parameters in …
Decreased activity of blood acid sphingomyelinase in the course of multiple myeloma
M Wątek, E Piktel, J Barankiewicz, E Sierlecka… - International journal of …, 2019 - mdpi.com
Acid sphingomyelinase (aSMase) is involved in the generation of metabolites that function
as part of the sphingolipid signaling pathway. It catalyzes the breakdown of sphingomyelin …
as part of the sphingolipid signaling pathway. It catalyzes the breakdown of sphingomyelin …
Palmitoylated importin-β1 transports miRNAs into exosomes via nSMase-dependent pathway
K Zen, Z Xu, Y Wei, DH Chen, S Qu, J Liu, H Liang… - 2024 - researchsquare.com
Extracellular miRNAs serve as an innovative category of signaling molecules facilitating
intercellular communication. Although the participation of AGO2 and other RNA-binding …
intercellular communication. Although the participation of AGO2 and other RNA-binding …
Characterization of S-palmitoylation dependent protein localization by hyperplexed spatial proteomics
M Stokkel - 2022 - studenttheses.uu.nl
S-Palmitoylation is a post translational modification (PTM) associated with numerous
cancers and neurological diseases. It is a reversible type of lipidation defined by the addition …
cancers and neurological diseases. It is a reversible type of lipidation defined by the addition …