[HTML][HTML] Proteogenomic analysis of chemo-refractory high-grade serous ovarian cancer

S Chowdhury, JJ Kennedy, RG Ivey, OD Murillo… - Cell, 2023 - cell.com
To improve the understanding of chemo-refractory high-grade serous ovarian cancers
(HGSOCs), we characterized the proteogenomic landscape of 242 (refractory and sensitive) …

Novel Pan-ERR agonists ameliorate heart failure through enhancing cardiac fatty acid metabolism and mitochondrial function

W Xu, C Billon, H Li, A Wilderman, L Qi, A Graves… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: Cardiac metabolic dysfunction is a hallmark of heart failure (HF). Estrogen-
related receptors ERRα and ERRγ are essential regulators of cardiac metabolism …

XDec-CHI reveals immunosuppressive interactions in pancreatic ductal adenocarcinoma

EL LaPlante, D Liu, V Petrosyan, Q Yao… - Iscience, 2022 - cell.com
Most cancers harbor a diverse collection of cell types including a typically heterogeneous
cancer cell fraction. To reconstruct cell-intrinsic and heterotypic interactions driving tumor …