The critically ill older patient with sepsis: a narrative review

M Ibarz, LEM Haas, A Ceccato, A Artigas - Annals of Intensive Care, 2024 - Springer
Sepsis is a significant public health concern, particularly affecting individuals above 70
years in developed countries. This is a crucial fact due to the increasing aging population …

Clinical sepsis phenotypes in critically ill patients

G Papathanakos, I Andrianopoulos, M Xenikakis… - Microorganisms, 2023 - mdpi.com
Sepsis, defined as the life-threatening dysregulated host response to an infection leading to
organ dysfunction, is considered as one of the leading causes of mortality worldwide …

Metformin attenuated sepsis-associated liver injury and inflammatory response in aged mice

H Song, X Zhang, R Zhai, H Liang, G Song, Y Yuan… - …, 2022 - Taylor & Francis
Sepsis-associated liver injury is with poor survival in intensive care units. Metformin is well
known for its therapeutic effects; however, its impact on treating liver injury due to sepsis …

Cluster analysis integrating age and body temperature for mortality in patients with sepsis: a multicenter retrospective study

MS Baek, JH Kim, YS Kwon - Scientific Reports, 2022 - nature.com
It is not clear whether mortality is associated with body temperature (BT) in older sepsis
patients. This study aimed to evaluate the mortality rates in sepsis patients according to age …

Development and validation of a score to predict mortality in ICU patients with sepsis: a multicenter retrospective study

J Weng, R Hou, X Zhou, Z Xu, Z Zhou, P Wang… - Journal of translational …, 2021 - Springer
Background Early and accurate identification of septic patients at high risk for ICU mortality
can help clinicians make optimal clinical decisions and improve the patients' outcomes. This …

U-Shaped association between serum calcium levels and 28-day mortality in patients with sepsis: a retrospective analysis of the MIMIC-III database

D Yan, X Xie, X Fu, S Pei, Y Wang, Y Deng… - Shock (Augusta …, 2023 - journals.lww.com
Background: Serum calcium levels disorder have been reported to be associated with poor
prognosis in different diseases. Studies on the association between serum calcium and …

Temperature control in sepsis

M Doman, M Thy, J Dessajan, M Dlela… - Frontiers in …, 2023 - frontiersin.org
Fever can be viewed as an adaptive response to infection. Temperature control in sepsis is
aimed at preventing potential harms associated with high temperature (tachycardia …

Prediction of 30-Day Mortality Using the Quick Pitt Bacteremia Score in Hospitalized Patients with Klebsiella pneumoniae Infection

C Su, IT Tsai, CH Lai, KH Lin, CC Chen… - Infection and drug …, 2023 - Taylor & Francis
Purpose Klebsiella pneumoniae is an important causative pathogen of nosocomial
infections, resulting in poor prognosis owing to its hypervirulence and antibiotic resistance. A …

Electroacupuncture at ST36 (Zusanli) Prevents T-Cell Lymphopenia and Improves Survival in Septic Mice

ZY Lv, YL Shi, GS Bassi, YJ Chen, LM Yin… - Journal of …, 2022 - Taylor & Francis
Purpose Sepsis is the main cause of death in intensive care unit. Maladaptive cytokine storm
and T-cell lymphopenia are critical prognosis predictors of sepsis. Electroacupuncture (EA) …

Screening Tool Risk Score Assessment in the Emergency Department for Geriatric (S-TRIAGE) in 28-day mortality

P Supatanakij, K Imok, K Suttapanit - International Journal of Emergency …, 2023 - Springer
Background The number of older adults with a high risk of frailty and severe illness
continues to increase. Moreover, physiological change and multiple comorbidities are …