[Retracted] Noscapine, an Emerging Medication for Different Diseases: A Mechanistic Review
P Rahmanian-Devin… - Evidence‐Based …, 2021 - Wiley Online Library
Noscapine is a benzylisoquinoline alkaloid isolated from poppy extract, used as an
antitussive since the 1950s, and has no addictive or euphoric effects. Various studies have …
antitussive since the 1950s, and has no addictive or euphoric effects. Various studies have …
The noscapine chronicle: a pharmaco‐historic biography of the opiate alkaloid family and its clinical applications
Given its manifold potential therapeutic applications and amenability to modification,
noscapine is a veritable “Renaissance drug” worthy of commemoration. Perhaps the only …
noscapine is a veritable “Renaissance drug” worthy of commemoration. Perhaps the only …
Poly (ethylene)-glycol conjugated solid lipid nanoparticles of noscapine improve biological half-life, brain delivery and efficacy in glioblastoma cells
Noscapine crosses blood–brain-barrier and inhibits proliferation of glioblastoma cells.
However, short plasma half-life and rapid elimination necessitate the administration of …
However, short plasma half-life and rapid elimination necessitate the administration of …
Comparative study of transfersomes, liposomes, and niosomes for topical delivery of 5-fluorouracil to skin cancer cells: preparation, characterization, in-vitro release …
Abstract Topical 5-fluorouracil (5-FU) is used for the treatment of actinic keratosis and
nonmelanoma skin cancer. Unfortunately, 5-FU per se shows a poor percutaneous …
nonmelanoma skin cancer. Unfortunately, 5-FU per se shows a poor percutaneous …
Biological evaluation of noscapine analogues as potent and microtubule-targeted anticancer agents
In present investigation, an attempt was undertaken to modify the C-9 position of noscapine
(Nos), an opium alkaloid to yield 9-hydroxy methyl and 9-carbaldehyde oxime analogues for …
(Nos), an opium alkaloid to yield 9-hydroxy methyl and 9-carbaldehyde oxime analogues for …
Fabrication of β-cyclodextrin and 2-hydroxypropyl-β-cyclodextrin inclusion complexes of Palbociclib: Physicochemical characterization, solubility enhancement, in …
P Paul, U Gupta, R Kumar, S Munagalasetty… - Journal of Molecular …, 2024 - Elsevier
Palbociclib (PAL) is an anti-cancer molecule that is highly selective for CDK4/6 inhibition
and approved for the management of advanced breast cancer. Due to its down-and-out …
and approved for the management of advanced breast cancer. Due to its down-and-out …
Soluble curcumin amalgamated chitosan microspheres augmented drug delivery and cytotoxicity in colon cancer cells: In vitro and in vivo study
K Jyoti, RK Bhatia, EAF Martis, EC Coutinho… - Colloids and Surfaces B …, 2016 - Elsevier
In present investigation, initially curcumin was complexed with 2-HP-β-CD (curcumin-2-HP-β-
CD-complex) in 1: 1 ratio and later amalgamated with chitosan microspheres (curcumin-2 …
CD-complex) in 1: 1 ratio and later amalgamated with chitosan microspheres (curcumin-2 …
Deciphering the binding mechanism of noscapine with lysozyme: biophysical and chemoinformatic approaches
Lysozyme is a well-characterized protein in terms of its structure, dynamics, and functions. It
has thus emerged as a potential target to understand protein–drug interactions. The aim of …
has thus emerged as a potential target to understand protein–drug interactions. The aim of …
A combinational approach towards treatment of breast cancer: an analysis of noscapine-loaded polymeric nanoparticles and doxorubicin
Our aim in this study was to clarify the combination anticancer effect of Noscapine (Nos)
loaded in a polymeric nanocarrier with Doxorubicin (Dox) on breast cancer cells …
loaded in a polymeric nanocarrier with Doxorubicin (Dox) on breast cancer cells …
Investigate the significance of DES to enhance the solubility of noscapine: DFT calculations, MD simulations, and experimental approach
MB Singh, A Prajapat, P Jain, A Kumar, P Singh… - Ionics, 2024 - Springer
In the present work, investigation of the choline chloride-urea base deep eutectic solvents
(DES) in various solvents has been performed to explore the change in interaction between …
(DES) in various solvents has been performed to explore the change in interaction between …