Taxonomic use of DNA G+ C content and DNA–DNA hybridization in the genomic age

JP Meier-Kolthoff, HP Klenk… - International journal of …, 2014 - microbiologyresearch.org
The G+ C content of a genome is frequently used in taxonomic descriptions of species and
genera. In the past it has been determined using conventional, indirect methods, but it is …

A polyphasic strategy incorporating genomic data for the taxonomic description of novel bacterial species

D Ramasamy, AK Mishra, JC Lagier… - … of systematic and …, 2014 - microbiologyresearch.org
Currently, bacterial taxonomy relies on a polyphasic approach based on the combination of
phenotypic and genotypic characteristics. However, the current situation is paradoxical in …

Scientific Guidance for the submission of dossiers on Food Enzymes

EFSA Panel on Food Contact Materials … - EFSA …, 2021 - Wiley Online Library
Following a request from the European Commission, EFSA developed an updated scientific
guidance to assist applicants in the preparation of applications for food enzymes. This …

[HTML][HTML] Genome-Based Taxonomic Classification of the Phylum Actinobacteria

I Nouioui, L Carro, M García-López… - Frontiers in …, 2018 - frontiersin.org
The application of phylogenetic taxonomic procedures led to improvements in the
classification of bacteria assigned to the phylum Actinobacteria but even so there remains a …

A new antibiotic kills pathogens without detectable resistance

LL Ling, T Schneider, AJ Peoples, AL Spoering… - Nature, 2015 - nature.com
Antibiotic resistance is spreading faster than the introduction of new compounds into clinical
practice, causing a public health crisis. Most antibiotics were produced by screening soil …

[HTML][HTML] Genome sequence-based species delimitation with confidence intervals and improved distance functions

JP Meier-Kolthoff, AF Auch, HP Klenk, M Göker - BMC bioinformatics, 2013 - Springer
Background For the last 25 years species delimitation in prokaryotes (Archaea and Bacteria)
was to a large extent based on DNA-DNA hybridization (DDH), a tedious lab procedure …

VICTOR: genome-based phylogeny and classification of prokaryotic viruses

JP Meier-Kolthoff, M Göker - Bioinformatics, 2017 - academic.oup.com
Motivation Bacterial and archaeal viruses are crucial for global biogeochemical cycles and
might well be game-changing therapeutic agents in the fight against multi-resistant …

Phylogenomics of Rhodobacteraceae reveals evolutionary adaptation to marine and non-marine habitats

M Simon, C Scheuner, JP Meier-Kolthoff… - The ISME …, 2017 - academic.oup.com
Abstract Marine Rhodobacteraceae (Alphaproteobacteria) are key players of
biogeochemical cycling, comprise up to 30% of bacterial communities in pelagic …

[HTML][HTML] Digital DNA-DNA hybridization for microbial species delineation by means of genome-to-genome sequence comparison

AF Auch, M von Jan, HP Klenk, M Göker - Standards in genomic sciences, 2010 - Springer
The pragmatic species concept for Bacteria and Archaea is ultimately based on DNA-DNA
hybridization (DDH). While enabling the taxonomist, in principle, to obtain an estimate of the …

[HTML][HTML] What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …