MYC, MYCL, and MYCN as therapeutic targets in lung cancer

D Masso-Valles, ME Beaulieu… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction: Lung cancer is the leading cause of cancer-related mortality globally. Despite
recent advances with personalized therapies and immunotherapy, the prognosis remains …

C-myc contributes to malignancy of lung cancer: a potential anticancer drug target

P Chanvorachote, N Sriratanasak… - Anticancer …, 2020 - ar.iiarjournals.org
Emerging evidence has provided important information on oncoproteins involved in cancer
initiation, progression, metastasis, and resistance to current therapies. C-myc, one of the …

Renal sarcoidosis

M Calatroni, G Moroni, F Reggiani, C Ponticelli - Journal of Nephrology, 2023 - Springer
Sarcoidosis is a systemic inflammatory disease of unknown etiology. The pathogenesis rests
on an aberrant T cell response to unidentified antigens in individuals predisposed by …

Sarcoidosis and calcium homeostasis disturbances—Do we know where we stand?

Ł Gwadera, AJ Białas, MA Iwański… - Chronic Respiratory …, 2019 - journals.sagepub.com
The majority of cases involving hypercalcemia in the setting of sarcoidosis are explained by
the overproduction of calcitriol by activated macrophages. Vitamin D takes part in the …

[HTML][HTML] Soluble sPD-L1 and serum amyloid A1 as potential biomarkers for lung cancer

D Jovanović, M Roksandić-Milenković… - Journal of Medical …, 2019 - ncbi.nlm.nih.gov
Background The objective of this prospective study was to evaluate whether soluble
programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) and serum amyloid …

Nutrition implications of intrinsic restrictive lung disease

S Rinaldi, C Balsillie, C Truchon… - Nutrition in Clinical …, 2022 - Wiley Online Library
Restrictive lung disease is defined as a reduction in lung volume that may be due to
intraparenchymal or extraparenchymal causes. Intraparenchymal causes falls under the …

[PDF][PDF] Osseous manifestations of sarcoidosis

EJ Kucharz - Reumatologia/Rheumatology, 2020 - termedia.pl
Sarcoidosis is a systemic multisystem inflammatory disease of unknown etiology. The
disease is characterized by formation of non-caseating granulomas. The most common …

[HTML][HTML] Association of overexpressed MYC gene with altered PHACTR3 and E2F4 genes contributes to non-small cell lung carcinoma pathogenesis

M Dragoj, J Bankovic, A Podolski-Renic… - Journal of medical …, 2019 - ncbi.nlm.nih.gov
Background C-Myc is one of the major cellular oncogenes overexpressed in non-small cell
lung carcinoma (NSCLC). Its deregulated expression is necessary but not sufficient for …

Vitamin D status and potential therapeutic options in critically ill patients: a narrative review of the clinical evidence

SL Cutuli, L Cascarano, ES Tanzarella, G Lombardi… - Diagnostics, 2022 - mdpi.com
Vitamin D covers roles of paramount importance in the regulation of multiple physiological
pathways of the organism. The metabolism of vitamin D involves kidney–liver crosstalk and …

Calcium, Phosphate, and Vitamin D Status in Patients with Sarcoidosis—Associations with Disease Activity and Symptoms

Ł Gwadera, AJ Białas, A Kumor-Kisielewska… - Journal of Clinical …, 2023 - mdpi.com
Sarcoidosis is a systemic granulomatous disease with a variety of presentations. One of the
known symptoms are altered vitamin D metabolism and hypercalcemia. In our study, we …