Apple derived cellulose scaffolds for 3D mammalian cell culture

DJ Modulevsky, C Lefebvre, K Haase, Z Al-Rekabi… - PloS one, 2014 - journals.plos.org
There are numerous approaches for producing natural and synthetic 3D scaffolds that
support the proliferation of mammalian cells. 3D scaffolds better represent the natural …

Mechanical cues direct focal adhesion dynamics

K Haase, Z Al-Rekabi, AE Pelling - Progress in molecular biology and …, 2014 - Elsevier
Focal adhesions play a fundamental role in force sensing, which influences a variety of
cellular processes and functions, particularly migration and the cell cycle. They consist of …

The role of cellular traction forces in deciphering nuclear mechanics

R Joshi, SB Han, WK Cho, DH Kim - Biomaterials Research, 2022 - spj.science.org
Cellular forces exerted on the extracellular matrix (ECM) during adhesion and migration
under physiological and pathological conditions regulate not only the overall cell …

Desmin modulates muscle cell adhesion and migration

C Hakibilen, F Delort, MT Daher, P Joanne… - Frontiers in Cell and …, 2022 - frontiersin.org
Cellular adhesion and migration are key functions that are disrupted in numerous diseases.
We report that desmin, a type-III muscle-specific intermediate filament, is a novel cell …

[HTML][HTML] Temperature-responsive poly (ε-caprolactone) cell culture platform with dynamically tunable nano-roughness and elasticity for control of myoblast morphology

K Uto, M Ebara, T Aoyagi - International journal of molecular sciences, 2014 - mdpi.com
We developed a dynamic cell culture platform with dynamically tunable nano-roughness
and elasticity. Temperature-responsive poly (ɛ-caprolactone)(PCL) films were successfully …

Enzyme‐free cell detachment mediated by resonance vibration with temperature modulation

Y Kurashina, M Hirano, C Imashiro… - Biotechnology and …, 2017 - Wiley Online Library
Cell detachment is an essential process in adherent cell culture. However, trypsinization,
which is the most popular detachment technique used in culture, damages cellular …

ROCK‐2 is associated with focal adhesion maturation during myoblast migration

KP Goetsch, C Snyman, KH Myburgh… - Journal of cellular …, 2014 - Wiley Online Library
Satellite cell migration is critical for skeletal muscle growth and regeneration. Controlled cell
migration is dependent on the formation of mature focal adhesions between the cell and the …

Role of integrin α7β1 signaling in myoblast differentiation on aligned polydioxanone scaffolds

MJ McClure, NM Clark, SL Hyzy, CE Chalfant… - Acta biomaterialia, 2016 - Elsevier
The aligned structural environment in skeletal muscle is believed to be a crucial component
in functional muscle regeneration. Myotube formation is increased on aligned biomaterials …

Cross talk between matrix elasticity and mechanical force regulates myoblast traction dynamics

Z Al-Rekabi, AE Pelling - Physical biology, 2013 - iopscience.iop.org
Growing evidence suggests that critical cellular processes are profoundly influenced by the
cross talk between extracellular nanomechanical forces and the material properties of the …

Intercellular adhesion molecule-1 augments myoblast adhesion and fusion through homophilic trans-interactions

FX Pizza, RA Martin, EM Springer, MS Leffler… - Scientific reports, 2017 - nature.com
The overall objective of the study was to identify mechanisms through which intercellular
adhesion molecule-1 (ICAM-1) augments the adhesive and fusogenic properties of …