Axonal transport: cargo-specific mechanisms of motility and regulation

S Maday, AE Twelvetrees, AJ Moughamian… - Neuron, 2014 - cell.com
Axonal transport is essential for neuronal function, and many neurodevelopmental and
neurodegenerative diseases result from mutations in the axonal transport machinery …

BDNF-induced local protein synthesis and synaptic plasticity

G Leal, D Comprido, CB Duarte - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …

Mitochondrial trafficking in neurons

TL Schwarz - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
Neurons, perhaps more than any other cell type, depend on mitochondrial trafficking for their
survival. Recent studies have elucidated a motor/adaptor complex on the mitochondrial …

[HTML][HTML] Molecular motors in neurons: transport mechanisms and roles in brain function, development, and disease

N Hirokawa, S Niwa, Y Tanaka - Neuron, 2010 - cell.com
The kinesin, dynein, and myosin superfamily molecular motors have fundamental roles in
neuronal function, plasticity, morphogenesis, and survival by transporting cargos such as …

Kinesin superfamily motor proteins and intracellular transport

N Hirokawa, Y Noda, Y Tanaka, S Niwa - Nature reviews Molecular cell …, 2009 - nature.com
Intracellular transport is fundamental for cellular function, survival and morphogenesis.
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …

[HTML][HTML] Theta burst stimulation of the human motor cortex

YZ Huang, MJ Edwards, E Rounis, KP Bhatia… - Neuron, 2005 - cell.com
It has been 30 years since the discovery that repeated electrical stimulation of neural
pathways can lead to long-term potentiation in hippocampal slices. With its relevance to …

Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences

AF Pedersen, DN Meyer, AMV Petriv, AL Soto… - Environmental …, 2020 - Elsevier
Microplastics (MPs) are a ubiquitous pollutant detected not only in marine and freshwater
bodies, but also in tap and bottled water worldwide. While MPs have been extensively …

[HTML][HTML] The molecular motor toolbox for intracellular transport

RD Vale - Cell, 2003 - cell.com
Eukaryotic cells create internal order by using protein motors to transport molecules and
organelles along cytoskeletal tracks. Recent genomic and functional studies suggest that …

[HTML][HTML] Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research?

KJ De Vos, M Hafezparast - Neurobiology of disease, 2017 - Elsevier
Intracellular trafficking of cargoes is an essential process to maintain the structure and
function of all mammalian cell types, but especially of neurons because of their extreme …

Phosphatidylinositol 3, 5-bisphosphate facilitates axonal vesicle transport and presynapse assembly

FS Rizalar, MT Lucht, A Petzoldt, S Kong, J Sun… - Science, 2023 - science.org
Neurons relay information via specialized presynaptic compartments for neurotransmission.
Unlike conventional organelles, the specialized apparatus characterizing the neuronal …