Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …

Metabolomics is the comprehensive assessment of endogenous metabolites and attempts to
systematically identify and quantify metabolites from a biological sample. Small-molecule …

Nonalcoholic steatohepatitis (NASH) prevalence is rising with no pharmacotherapy
approved. A major hurdle in NASH drug development is the poor translatability of preclinical …

Mass spectrometry (MS) and nuclear magnetic resonance (NMR) have evolved as the most
common techniques in metabolomics studies, and each brings its own advantages and …

Metabolomics has advanced significantly in the past 10 years with important developments
related to hardware, software and methodologies and an increasing complexity of …

Urinary tests have been used as noninvasive, cost-effective tools for screening, diagnosis
and monitoring of diseases since ancient times. As we progress through the 21st century …

Introduction The pattern of exhaled breath volatile organic compounds represents a
metabolic biosignature with the potential to identify and characterize lung cancer. Breath …

Early diagnosis of oral squamous cell carcinoma (OSCC) is an attractive strategy to increase
survival rate of patient. An integrated separation approach of reversed phase liquid …

Systems biology has primarily focused on studying genomics, transcriptomics, and
proteomics and their dynamic interactions. These, however, represent only the potential for a …

Metabolomics, the systematic investigation of all metabolites present within a biologic
system, is used in biomarker development for many human diseases, including cancer. In …