Nucleic acid sequencing

T Hauling, M Kühnemund - US Patent 11,352,667, 2022 - Google Patents
A nucleic acid sequencing method involving contacting a spatially defined target nucleic
acid sequence with N labeled oligonucleotide probes and performing measurements, at …

Highly-multiplexed fluorescent imaging

GP Nolan, N Samusik, J Kennedy-Darling… - US Patent …, 2021 - Google Patents
Provided herein is a method and system for analyzing a sample. In some embodiments the
method makes use of a plurality of capture agents that are each linked to a different …

Highly-multiplexed fluorescent imaging

GP Nolan, N Samusik, J Kennedy-Darling… - US Patent …, 2019 - Google Patents
Provided herein is a method and system for analyzing a sample. In some embodiments the
method makes use of a plurality of capture agents that are each linked to a different …

On-slide staining by primer extension

N Samusik, GP Nolan, Y Goltsev - US Patent 9,909,167, 2018 - Google Patents
A method for analyzing planar sample is provided. In some cases the method comprises:(a)
incubating the planar sample with a capture agent that is linked to an oligonucleotide …

Methods for preparing high-resolution spatial arrays

FA Bava - US Patent 12,110,541, 2024 - Google Patents
Provided herein are methods of preparing a spatial array and methods for associating
specific sample analytes with spatial locations in the spatial array. Provided herein are …

Increasing efficiency of spatial analysis in a biological sample

FA Bava - US Patent 11,732,300, 2023 - Google Patents
Disclosed herein are methods of amplifying an analyte in a biological sample using a
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …

Increasing capture efficiency of spatial assays

FA Bava - US Patent 11,898,205, 2024 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …

Generating capture probes for spatial analysis

Y Yin, EPR Iyer, Z Bent, S Giacomello… - US Patent …, 2023 - Google Patents
2021-06-10 Assigned to 10X GENOMICS, INC. reassignment 10X GENOMICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …

Methods for printing cells and generating arrays of barcoded cells

R Bharadwaj - US Patent 11,702,693, 2023 - Google Patents
US11702693B2 - Methods for printing cells and generating arrays of barcoded cells -
Google Patents US11702693B2 - Methods for printing cells and generating arrays of …

Spatial assays with perturbed cells

EPR Iyer - US Patent 11,732,299, 2023 - Google Patents
US11732299B2 - Spatial assays with perturbed cells - Google Patents US11732299B2 -
Spatial assays with perturbed cells - Google Patents Spatial assays with perturbed cells Info …