Recent advances in the synthesis of fluoroalkylated compounds using fluoroalkyl anhydrides

W Wu, Y You, Z Weng - Chinese Chemical Letters, 2022 - Elsevier
Fluoroalkyl-containing organic compounds have exhibited wide applications in the field of
pharmaceuticals, agrochemicals and materials science due to their outstanding properties …

Modern methods for the synthesis of perfluoroalkylated aromatics

DJ Castillo-Pazos, JD Lasso, CJ Li - Organic & Biomolecular …, 2021 - pubs.rsc.org
Perfluoroalkyl-containing substances (PFAS), have become omnipresent materials in the
modern world for both commercial and research applications. Compounds such as …

Metallaphotoredox Perfluoroalkylation of Organobromides

X Zhao, DWC MacMillan - Journal of the American Chemical …, 2020 - ACS Publications
Ruppert–Prakash type reagents (TMSCF3, TMSC2F5, and TMSC3F7) are readily available,
air-stable, and easy-to-handle fluoroalkyl sources. Herein, we describe a mild, copper …

Transition‐Metal‐Free Direct Trifluoromethylation and Perfluoroalkylation of Imidazopyridines under Mild Conditions

S Han, X Gao, Q Wu, J Li, D Zou… - Advanced Synthesis & …, 2019 - Wiley Online Library
The first transition‐metal‐free method for direct C− H trifluoromethylation of imidazo [1, 2‐a]
pyridine derivatives with readily available Ruppert‐Prakash reagent TMSCF3 under mild …

Transition-metal-free direct perfluoroalkylation of quinoline amides at C5 position through radical cross-coupling under mild conditions

J Xu, L Qiao, B Ying, X Zhu, C Shen… - Organic Chemistry …, 2017 - pubs.rsc.org
A simple and efficient method is established for the synthesis of perfluoroalkylated
quinolines in the absence of any transition metal catalysts. The eco-friendly reaction reveals …

Photocatalytic reductive fluoroalkylation of nitrones

VI Supranovich, VV Levin, MI Struchkova… - Organic letters, 2018 - ACS Publications
A method for the addition of fluorinated groups to nitrones using an iridium photocatalyst and
ascorbic acid as a stoichiometric reducing agent is described. The reaction proceeds …

Metal-free synthesis of 2-fluoroalkylated quinolines using polyfluoroalkanoic acids as direct fluorine sources

J Nan, Y Hu, P Chen, Y Ma - Organic letters, 2019 - ACS Publications
A novel [5+ 1] cyclization of 2-vinylanilines with polyfluoroalkanoic acids under catalyst-and
additive-free conditions was successfully implemented. The approach directly employs very …

Rhenium‐Catalyzed Decarboxylative Tri‐/Difluoromethylation of Styrenes with Fluorinated Carboxylic Acid‐Derived Hypervalent Iodine Reagents

Y Wang, Y Yang, C Wang - Chinese Journal of Chemistry, 2019 - Wiley Online Library
Summary of main observation and conclusion Herein, unprecedented rhenium‐catalyzed
decarboxylative oxytri‐/difluoromethylation and Heck‐type trifluoromethylation of styrenes …

Recent advances on non-precious metal-catalysed fluorination, difluoromethylation, trifluoromethylation, and perfluoroalkylation of N-heteroarenes

A Bera, D Banerjee - Organic & Biomolecular Chemistry, 2023 - pubs.rsc.org
This review highlights the recent advances, from 2015 to 2023, on the introduction of organo-
fluorine derivatives at the N-heteroarene core. Notable features considering new …

Synthesis of 4-trifluoromethyl 2-pyrones and pyridones through the Brønsted base-catalyzed Pechmann-type reaction with cyclic 1, 3-diones

W Yan, R Wang, T Zhang, H Deng, J Chen… - Organic & …, 2018 - pubs.rsc.org
An efficient method for the synthesis of 4-trifluoromethyl 2-pyrones through the Brønsted
base-catalyzed Pechmann-type reaction of cyclic 1, 3-diones with ethyl 4, 4, 4 …