Cytochrome P450 pharmacogenetics in African populations: implications for public health

C Dandara, M Swart, B Mpeta, A Wonkam… - Expert opinion on …, 2014 - Taylor & Francis
Introduction: Africa harbors a disproportionate burden of disease when taking into account
the triple challenge caused by HIV/AIDS, tuberculosis (TB) and malaria, against a backdrop …

Pharmacogenetics of breast cancer treatments: a sub-Saharan Africa perspective

KC Nthontho, AK Ndlovu, K Sharma… - Pharmacogenomics …, 2022 - Taylor & Francis
Breast cancer is the most frequent cause of cancer death in low-and middle-income
countries, in particular among sub-Saharan African women, where response to available …

Knowledge of pharmacogenetics among healthcare professionals and faculty members of health training institutions in Ghana

W Kudzi, BS Addy, B Dzudzor - Ghana medical journal, 2015 - ajol.info
Background: Pharmacogenetics has a potential for optimizing drug response and identifying
risk of toxicity for patients. Pharmacogenetics knowledge of healthcare professionals and the …

Pharmacogenetics in clinical practice: current level of knowledge among Flemish physicians and pharmacists

A Edris, A Vanoverschelde, P Bushaj… - The …, 2021 - nature.com
Over the past decade, pharmacogenetics (PGx) became an essential tool for personalized
medicine although its clinical implementation is still limited. We aimed to assess the current …

Pharmacogenomics and Public Health: Implementing 'populationalized 'Medicine

L Mette, K Mitropoulos, A Vozikis… - Pharmacogenomics, 2012 - Taylor & Francis
Pharmacogenomics are frequently considered in personalized medicine to maximize
therapeutic benefits and minimize adverse drug reactions. However, there is a movement …

Population pharmacogenomics: Impact on public health and drug development

GP Patrinos - Pharmacogenomics, 2018 - Taylor & Francis
In humans, like every other organism, there is huge interindividual variability, resulting in
approximately 3.5–5 million naturally occurring genomic variants observed per genome …

[HTML][HTML] Detección de reacciones adversas a medicamentos metabolizados por el Citocromo P4502C9

M Álvarez Corredera, Y Cervelo Fernández… - Revista Cubana de …, 2015 - scielo.sld.cu
Introducción: la existencia de variaciones interindividuales en la respuesta a los
medicamentos es multifactorial e incluye la genética y el medio ambiente por tanto, en la …

Prostate Cancer Prevention in the Developing World-What are we Waiting for?

KS Bishop, CHJ Kao, DY Han… - Current …, 2012 - ingentaconnect.com
The field of personalized medicine is currently broadening in scope in at least three crucial
dimensions. First, while genetics/genomics individual variability is an important aspect of …

Leveraging Machine Learning for Precision Medicine In Ghana

NKM Sarpong - 2024 - air.ashesi.edu.gh
Precision medicine, empowered by machine learning, has made substantial strides in
developed countries, yet its implementation in Ghana faces substantial challenges due to …

Pharmacogenetics: Relevance to african healthcare

N J. Roetz, L Warnich - Current Pharmacogenomics and …, 2013 - benthamdirect.com
Sequencing the human genome, more than a decade ago, initiated the genomics era and
the promise of truly personalized medicine. However, much is still unknown about the …