Cell cycle regulation and the NF-κB pathway in cancer cells are important in mediating
resistance to 5-Fluorouracil (5-FU). Pentagamavunon-1 (PGV-1), a curcumin analog, is …

Purpose: Breast cancer cells with overexpression of HER2 are known to be more
aggressive, invasive, and resistant to chemotherapeutic agent. Brazilin, the major compound …

Genistein (Gen) demonstrates growth induction and inhibition on several cancer cells
depending on the dose. By using triple-negative breast cancer metastatic cells, 4T1, this …

Breast cancer therapy with classical chemotherapy is unable to eradicate breast cancer
stem cells (BCSCs). Loss of p53 function causes growth and differentiation in cancer stem …

Theacrine, a purine alkaloid structurally similar to caffeine, has recently become of interest
as a potential therapeutic compound. Here, we investigated the antimetastatic potential of …

Prostate cancer is one of the leading cancers in men, and new approaches are needed for
its treatment. The aim of this study was to investigate the effect of co-administration of …

Breast cancer is the main cause of cancer death among women, especially breast cancer
metastasis. Metastasis process begins with the ability of cell cancer invasion. Doxorubicin, a …

Abstract Background Hesperetin (Hst), a citrus flavanone, is widely distributed among citrus
fruits, including lemons. Hst has been shown to possess bioactivity as an antioxidant, anti …

Six novel bridged structure cyclotriphosphazenes (4a-f) were synthesized from the reactions
of aryloxycyclotriphosphazenes [aryloxy= phenoxy (2a) and (2-naphthoxy)(2b)] with …

Objectives: Pyrophen, an amino acid-pyrone derivative isolated from Aspergillus fumigatus
strain KARSV04 has been reported to have an anticancer effect on T47D cells by inhibiting …