The response to neoadjuvant chemoradiation (nCRT) is a critical step in the management of
locally advanced rectal cancer (LARC) patients. Only a minority of LARC patients responds …

Introduction To date, all efforts to fight gastrointestinal cancer, regardless of its origin and
entity, have resulted in complex therapeutic regimens involving a combination of systemic …

Simple Summary Around 15% of locally advanced rectal cancer patients have positive
lateral pelvic lymph-nodes at diagnosis, with a worse prognosis due to the high incidence of …

Aim A 'watch and wait'(W&W) strategy after neoadjuvant long‐course chemoradiotherapy
(NACRT) remains controversial. Whilst encouraging short‐term data exist, the strategy will …

Aim To evaluate the pattern of tumor relapse of pathological complete response (pCR)
patients with locally advanced rectal cancer (LARC) following neoadjuvant …

Background Radical resection is typically the standard treatment for early-and mid-stage
rectal cancer as local resection may result in a high rate of recurrence and risk of distant …

Neoadjuvant chemoradiotherapy followed by surgical resection is the standard of care for
locally advanced rectal adenocarcinoma. Up to one third of patients achieve pathologic …

Background: Our aim was to compare the bowel function and oncologic outcomes following
these two treatment modalities. Materials and methods: This was a single-center study with …

Background Watch-and-wait strategy has been increasingly accepted for patients with
clinical complete response (cCR) after multimodal treatment for locally advanced rectal …

Background Management of rectal cancer has a number of potentially appropriate
alternatives for each patient. Despite acceptance of standards, practices may vary among …