Multidrug resistance in Escherichia coli has become a worrying issue that is increasingly
observed in human but also in veterinary medicine worldwide. E. coli is intrinsically …

Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

This work aims to evaluate the antimicrobial potential of ethanolic and water extracts of
roselle (Hibiscus sabdariffa), rosemary (Rosmarinus officinalis), clove (Syzygium …

Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …

The dramatic global rise of MDR and XDR Enterobacterales in human medicine forced
clinicians to the reintroduction of colistin as last-resort drug. Meanwhile, colistin is used in …

Antibiotic resistance has become a global public health priority. Polymyxins, a family of
cationic polypeptide antibiotics, act as a final line of refuge against severe infections by …

Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …

Polymyxins have recently been re-introduced into the therapeutic arsenal to combat
infections caused by multidrug-resistant Gram-negative bacteria. However, the emergence …

Antimicrobial agents are used in both veterinary and human medicine. The intensive use of
antimicrobials in animals may promote the fixation of antimicrobial resistance genes in …

Polymyxins are the last line of defense against lethal infections caused by multidrug
resistant Gram-negative pathogens. Very recently, the use of polymyxins has been greatly …