Stroke, the third leading cause of death and disability worldwide, is undergoing a change in
perspective with the emergence of new ideas on neurodegeneration. The concept that …

Increasing evidence indicates a possible causal link between neuroinflammation and
neurological disorders, including Alzheimer's disease (AD), Parkinson's disease (PD) …

Nanotechnology-mediated antioxidative therapy is emerging as a novel strategy for treating
a myriad of important diseases through scavenging excessive reactive oxygen and nitrogen …

Ischemic stroke is a devastating disease and one of the leading causes of mortality
worldwide. Overproduction of reactive oxygen and nitrogen species (RONS) following …

Inflammation clearly occurs in pathologically vulnerable regions of the Alzheimer's disease
(AD) brain, and it does so with the full complexity of local peripheral inflammatory responses …

Brain injury following transient or permanent focal cerebral ischaemia (stroke) develops from
a complex series of pathophysiological events that evolve in time and space. In this article …

This review is directed at understanding how neuronal death occurs in two distinct insults,
global ischemia and focal ischemia. These are the two principal rodent models for human …

The highly disagreeable sensation of pain results from an extraordinarily complex and
interactive series of mechanisms integrated at all levels of the neuroaxis, from the periphery …

Recent works in the area of stroke and brain ischemia has demonstrated the significance of
the inflammatory response accompanying necrotic brain injury. Acutely, this response …

There is an urgent need for improved diagnostics and therapeutics for acute ischemic stroke.
This is the focus of numerous research projects involving in vitro studies, animal models and …