Benralizumab: a unique IL-5 inhibitor for severe asthma

LD Tan, JM Bratt, D Godor, S Louie… - Journal of Asthma and …, 2016 - Taylor & Francis
The presence of eosinophilic inflammation is a characteristic feature of chronic and acute
inflammation in asthma. An estimated 5%–10% of the 300 million people worldwide who …

Consensus on the asthma–COPD overlap (ACO) between the Spanish COPD guidelines (GesEPOC) and the Spanish guidelines on the management of asthma …

V Plaza, F Álvarez, M Calle, C Casanova… - Archivos de …, 2017 - Elsevier
Following a proposal by the Spanish Society of Pulmonology and Thoracic Surgery
(SEPAR), sponsor of the Spanish COPD Guidelines (GesEPOC) and the Spanish …

The asthma–COPD overlap syndrome: do we really need another syndrome in the already complex matrix of airway disease?

K Kostikas, A Clemens, F Patalano - International journal of chronic …, 2016 - Taylor & Francis
The term asthma–COPD overlap syndrome (ACOS) is one of multiple terms used to describe
patients with characteristics of both COPD and asthma, representing~ 20% of patients with …

Algorithm for identification of asthma–COPD overlap: consensus between the Spanish COPD and asthma guidelines

M Miravitlles, FJ Alvarez-Gutierrez… - European …, 2017 - Eur Respiratory Soc
It was as early as 1959 that the report of the CIBA Symposium described the possible
coexistence of different obstructive airway diseases, such as asthma, chronic bronchitis …

Incidence and long-term outcome of severe asthma–COPD overlap compared to asthma and COPD alone: a 35-year prospective study of 57,053 middle-aged adults

CB Baarnes, ZJ Andersen, A Tjønneland… - International journal of …, 2017 - Taylor & Francis
Background Incidence and prognosis for severe asthma–COPD overlap is poorly
characterized. We investigated incidence and long-term outcome for patients with asthma …

The mechanisms of the regulation of immune response in patients with comorbidity of chronic obstructive pulmonary disease and asthma

EP Kalinina, YK Denisenko, TI Vitkina… - Canadian respiratory …, 2016 - Wiley Online Library
Background. Comorbidity of chronic obstructive pulmonary disease (COPD) and asthma
(asthma COPD overlap syndrome, ACOS) is a significant problem in pulmonary practice …

Characteristics of COPD patients managed in respiratory medicine departments in Spain, according to GOLD groups and GesEPOC clinical phenotypes

JL Izquierdo, M Miravitlles, C Esquinas, M Pérez… - Archivos de …, 2018 - Elsevier
Introduction The objective of this study was to analyze the clinical characteristics of COPD
patients attending general respiratory clinics, adherence to clinical guidelines, classification …

Consenso sobre el solapamiento de asma y EPOC (ACO) entre la Guía española de la EPOC (GesEPOC) y la Guía Española para el Manejo del Asma (GEMA)

V Plaza, F Álvarez, M Calle, C Casanova… - Archivos de …, 2017 - Elsevier
A instancias de la Sociedad Española de Neumología y Cirugía Torácica (SEPAR),
promotora de la Guía española de la EPOC (GesEPOC) y de la Guía Española para el …

Value of exhaled nitric oxide (FeNO) and eosinophilia during the exacerbations of chronic obstructive pulmonary disease requiring hospital admission

MT Río Ramírez, MA Juretschke Moragues… - COPD: Journal of …, 2018 - Taylor & Francis
The aim of this study was to analyze whether FeNO levels in acute exacerbation of COPD
(AECOPD) with hospital admission have better diagnostic value than eosinophilia in blood …

[HTML][HTML] Asthma-chronic obstructive pulmonary disease overlap syndrome–Literature review and contributions towards a Portuguese consensus

D Araújo, E Padrão, M Morais-Almeida… - Revista Portuguesa de …, 2017 - Elsevier
Introduction Phenotypic overlap between the two main chronic airway pulmonary diseases,
asthma and chronic obstructive pulmonary disease (COPD), has been the subject of debate …