Soft matter exhibits a multitude of intrinsic physico-chemical attributes. Their mechanical
properties are crucial characteristics to define their performance. In this context, the rigidity of …

Biological phase separation is known to be important for cellular organization, which has
recently been extended to a new class of biomolecules that form liquid-like droplets …

Biomolecular condensates play a key role in organizing cellular fluids such as the cytoplasm
and nucleoplasm. Most of these non-membranous organelles show liquid-like properties …

Multivalent protein-protein and protein-RNA interactions are the drivers of biological phase
separation. Biomolecular condensates typically contain a dense network of multiple proteins …

Cells are compartmentalized by numerous membrane-enclosed organelles and
membraneless compartments to ensure that a wide variety of cellular activities occur in a …

Liquid–liquid phase separation (LLPS) of proteins underlies the formation of membrane-less
organelles. While it has been recognized for some time that these organelles are of key …

Cells contain numerous membraneless organelles that assemble by intracellular liquid-
liquid phase separation. The viscous properties and associated biomolecular mobility within …

Liquid–liquid phase separation (LLPS) is an emerging and universal mechanism for
intracellular organization, particularly, by forming membraneless organelles (MLOs) hosting …

Microtubule-associated protein tau is characterized by the fact that it is an intrinsically
disordered protein due to its lack of a stable conformation and high flexibility. Intracellular …

Aberrant phase separation of globular proteins is associated with many diseases. Here, we
use a model protein system to understand how the unfolded states of globular proteins drive …