[HTML][HTML] HPV infections—classification, pathogenesis, and potential new therapies

B Mlynarczyk-Bonikowska, L Rudnicka - International Journal of …, 2024 - mdpi.com
To date, more than 400 types of human papillomavirus (HPV) have been identified. Despite
the creation of effective prophylactic vaccines against the most common genital HPVs, the …

mRNA-LNP vaccination-based immunotherapy augments CD8+ T cell responses against HPV-positive oropharyngeal cancer

K Qiu, X Duan, M Mao, Y Song, Y Rao, D Cheng… - npj Vaccines, 2023 - nature.com
Although mRNA vaccines are known as potent activators of antigen-specific immune
responses against infectious diseases, limited understanding of how they drive the …

Human papillomavirus associated cervical lesion: pathogenesis and therapeutic interventions

J Ye, L Zheng, Y He, X Qi - MedComm, 2023 - Wiley Online Library
Human papillomavirus (HPV) is the most prevalent sexually transmitted virus globally.
Persistent high‐risk HPV infection can result in cervical precancerous lesions and cervical …

Roles of human papillomavirus in cancers: oncogenic mechanisms and clinical use

Y Zhang, K Qiu, J Ren, Y Zhao, P Cheng - Signal Transduction and …, 2025 - nature.com
Human papillomaviruses, particularly high-risk human papillomaviruses, have been
universally considered to be associated with the oncogenesis and progression of various …

Advancing Tumor Vaccines: Overcoming TME Challenges, Delivery Strategies, and Biomaterial-based Vaccine for Enhanced Immunotherapy

Q Zeng, S Zhang, N Leng, Y Xing - Critical Reviews in Oncology …, 2024 - Elsevier
Tumor vaccines, as an immunotherapeutic approach, harness the body's immune cells to
provoke antitumor responses, which have shown promising efficacy in clinical settings …

Progress in the treatment of anal cancer: an overview of the latest investigational drugs

J Yu, RD Kim - Expert Opinion on Investigational Drugs, 2024 - Taylor & Francis
Introduction Anal cancer, a rare malignancy accounting for 2.5–3.0% of gastrointestinal
cancers, primarily manifests as squamous cell carcinoma associated with HPV. Recent …

[HTML][HTML] Advancing the Fight Against Cervical Cancer: The Promise of Therapeutic HPV Vaccines

Q Zheng, M He, Z Mao, Y Huang, X Li, L Long, M Guo… - Vaccines, 2025 - mdpi.com
Human papillomavirus (HPV) is a major global health issue and is recognized as the
leading cause of cervical cancer. While prophylactic vaccination programs have led to …

Preclinical Immunogenicity and Efficacy Studies for Therapeutic Vaccines for Human Papillomavirus-Type-16-Associated Cancer

M Mohammadi, A Saha, W Giles-Davis, Z Xiang… - Vaccines, 2024 - mdpi.com
The objective of this study was to conduct preclinical immunogenicity and efficacy studies
with several therapeutic vaccines for human papillomavirus (HPV)-16-associated cancers …

Tumor-infiltrating plasma cells are a prognostic factor in penile squamous cell carcinoma

PJ Stenzel, A Thomas, M Schindeldecker… - Virchows Archiv, 2025 - Springer
Penile cancer (PeCa) is a rare disease with poor prognosis in the metastatic stage. Neither
effective adjuvant nor palliative therapeutic options are available. Research efforts in this …

[HTML][HTML] Sintilimab plus HPV vaccine for recurrent or metastatic cervical cancer

B Wang, Y Liang, Y Wu, Q Li, Y Zeng… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Purpose Recurrent or metastatic cervical cancer (r/m CC) presents limited treatment options
for patients failed or progressed quickly following first-line therapy. This study investigated …