A multilayered immune system through the lens of unconventional T cells
The unconventional T cell compartment encompasses a variety of cell subsets that straddle
the line between innate and adaptive immunity, often reside at mucosal surfaces and can …
the line between innate and adaptive immunity, often reside at mucosal surfaces and can …
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
B Afzali, G Lombardi, RI Lechler… - Clinical & Experimental …, 2007 - academic.oup.com
Summary Uncommitted (naive) murine CD4+ T helper cells (Thp) can be induced to
differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (Treg) phenotypes …
differentiate towards T helper 1 (Th1), Th2, Th17 and regulatory (Treg) phenotypes …
Regulatory lymphocytes and intestinal inflammation
A Izcue, JL Coombes, F Powrie - Annual review of immunology, 2009 - annualreviews.org
The immune system is pivotal in mediating the interactions between host and microbiota that
shape the intestinal environment. Intestinal homeostasis arises from a highly dynamic …
shape the intestinal environment. Intestinal homeostasis arises from a highly dynamic …
[HTML][HTML] Regulation of activated CD4+ T cells by NK cells via the Qa-1–NKG2A inhibitory pathway
L Lu, K Ikizawa, D Hu, MBF Werneck… - Immunity, 2007 - cell.com
The ability of natural-killer cells to regulate adaptive immunity is not well understood. Here
we define an interaction between the class Ib major histocompatibility complex (MHC) …
we define an interaction between the class Ib major histocompatibility complex (MHC) …
Revival of CD8+ Treg–mediated suppression
TRF Smith, V Kumar - Trends in immunology, 2008 - cell.com
Despite their first recognition almost 40 years ago, CD8+'suppressor'T cells remain poorly
characterized. Recent studies of these lymphocytes, now popularly referred to as regulatory …
characterized. Recent studies of these lymphocytes, now popularly referred to as regulatory …
Small intestinal CD8+TCRγδ+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease
Intraepithelial lymphocytes (IELs) bearing the γδ TCR are more abundant in the small
intestinal mucosa of patients with celiac disease (CD) compared with healthy individuals …
intestinal mucosa of patients with celiac disease (CD) compared with healthy individuals …
Pathways of major histocompatibility complex allorecognition
B Afzali, G Lombardi, RI Lechler - Current opinion in organ …, 2008 - journals.lww.com
Pathways of major histocompatibility complex allorecognition : Current Opinion in Organ
Transplantation Pathways of major histocompatibility complex allorecognition : Current Opinion …
Transplantation Pathways of major histocompatibility complex allorecognition : Current Opinion …
Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells
Abstract OTHER ARTICLES PUBLISHED IN THIS MINI-REVIEW SERIES ON Th17 CELLS
Function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol …
Function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol …
The immunology of multiple sclerosis
A Bar-Or - Seminars in neurology, 2008 - thieme-connect.com
Recent years have witnessed a remarkable growth in literature related to the biology and
treatment of multiple sclerosis (MS). The focus of this article is on aspects of the human …
treatment of multiple sclerosis (MS). The focus of this article is on aspects of the human …
Essential role of CD8+ CD122+ regulatory T cells in the recovery from experimental autoimmune encephalomyelitis
Experimental autoimmune encephalomyelitis (EAE) is one of the best-documented animal
models of autoimmune disease. We examined the role of CD8+ CD122+ regulatory T cells …
models of autoimmune disease. We examined the role of CD8+ CD122+ regulatory T cells …