Stroke is the leading cause of disability and thesecond leading cause of death worldwide.
With the global population aged 65 and over growing faster than all other age groups, the …

The vascular endothelium is a multifunctional organ and is critically involved in modulating
vascular tone and structure. Endothelial cells produce a wide range of factors that also …

Homeostasis of energy is regulated by genetic factors, food intake, and energy expenditure.
When energy input is greater than expenditure, the balance is positive, which can lead to …

Adropin is a secreted peptide that improves hepatic steatosis and glucose homeostasis
when administered to diet‐induced obese mice. It is not clear if adropin is a peptide …

Adropin is a novel 76-amino acid-peptide that is expressed in different tissues and cells
including the liver, pancreas, heart and vascular tissues, kidney, milk, serum, plasma and …

Pyruvate dehydrogenase kinase (PDK) can regulate the catalytic activity of pyruvate
decarboxylation oxidation via the mitochondrial pyruvate dehydrogenase complex, and it …

Objective The peptide hormone adropin regulates fuel selection preferences in skeletal
muscle under fed and fasted conditions. Here, we investigated whether adropin treatment …

Context: Mouse studies suggest that adropin, a peptide hormone, is required for metabolic
homeostasis and prevention of obesity-associated insulin resistance. Whether obesity and …

Aging-induced arterial stiffening is reduced by aerobic exercise training, and elevated
production of nitric oxide (NO) participates in this effect. Adropin is a regulator of endothelial …

The endothelium regulates vascular tone, platelet activity, leukocyte adhesion, and
angiogenesis by producing nitric oxide and other regulatory factors. Risk factors decrease …