Exosome-associated hepatitis C virus in cell cultures and patient plasma

Z Liu, X Zhang, Q Yu, JJ He - Biochemical and biophysical research …, 2014 - Elsevier
Hepatitis C virus (HCV) infects its target cells in the form of cell-free viruses and through cell–
cell contact. Here we report that HCV is associated with exosomes. Using highly purified …

Mouse hepatic cells support assembly of infectious hepatitis C virus particles

G Long, MS Hiet, MP Windisch, JY Lee, V Lohmann… - Gastroenterology, 2011 - Elsevier
BACKGROUND & AIMS: Hepatitis C virus (HCV) has a high propensity to establish
persistence; better understanding of this process requires the development of a fully …

Replication of subgenomic hepatitis C virus replicons in mouse fibroblasts is facilitated by deletion of interferon regulatory factor 3 and expression of liver-specific …

LT Lin, RS Noyce, TNQ Pham, JA Wilson… - Journal of …, 2010 - Am Soc Microbiol
Hepatitis C virus (HCV) infection causes significant morbidity, and efficient mouse models
would greatly facilitate virus studies and the development of effective vaccines and new …

Zebrafish as a potential model organism for drug test against hepatitis C virus

CB Ding, JP Zhang, Y Zhao, ZG Peng, DQ Song… - PloS one, 2011 - journals.plos.org
Screening and evaluating anti-hepatitis C virus (HCV) drugs in vivo is difficult worldwide,
mainly because of the lack of suitable small animal models. We investigate whether …

A zebrafish model for subgenomic hepatitis C virus replication

CB Ding, Y Zhao, JP Zhang… - International …, 2015 - spandidos-publications.com
Persistent infection with hepatitis C virus (HCV) is a major risk factor in the development of
hepatocellular carcinoma. The elucidation of the pathogenesis of HCV-associated liver …

Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus

JM Gaska, M Balev, Q Ding, B Heller, A Ploss - Elife, 2019 - elifesciences.org
The restricted host tropism of hepatitis C virus (HCV) remains incompletely understood,
especially post-entry, and has hindered developing an immunocompetent, small animal …

[图书][B] Characterization of hepatitis C virus infection of hepatocytes and astrocytes

Z Liu - 2014 - search.proquest.com
Abstract Approximately 2.8% of the world population is currently infected with hepatitis C
virus (HCV). Neutralizing antibodies (nAbs) are often generated in chronic hepatitis C …

[PDF][PDF] REPLICATION OF HEPATITIS C VIRUS FULL-LENGTH GENOME IN MOUSE CELLS REQUIRES ADDITIONAL HOST FACTORS BESIDES MICRORNA-122

LT Lin, CD Richardson - HOST FACTOR REGULATION OF …, 2010 - dam-oclc.bac-lac.gc.ca
Hepatitis C virus (HCV) establishes chronic infection that causes significant morbidity
associated with end-stage liver disease. Generation of a convenient mouse model capable …

[PDF][PDF] Replication of Subgenomic HCV Replicons in Mouse Fibroblasts is Facilitated by Deletion of Interferon Regulatory Factor-3 and Expression of

LS MicroRNA - 2010 - Citeseer
ABSTRACT 1 Hepatitis C virus (HCV) infection causes significant morbidity, and efficient
mouse models 2 would greatly facilitate virus studies and the development of effective …