Structural components of synaptic plasticity and memory consolidation

CH Bailey, ER Kandel… - Cold Spring Harbor …, 2015 - cshperspectives.cshlp.org
Consolidation of implicit memory in the invertebrate Aplysia and explicit memory in the
mammalian hippocampus are associated with remodeling and growth of preexisting …

Kinesin superfamily motor proteins and intracellular transport

N Hirokawa, Y Noda, Y Tanaka, S Niwa - Nature reviews Molecular cell …, 2009 - nature.com
Intracellular transport is fundamental for cellular function, survival and morphogenesis.
Kinesin superfamily proteins (also known as KIFs) are important molecular motors that …

[HTML][HTML] mRNA localization: gene expression in the spatial dimension

KC Martin, A Ephrussi - Cell, 2009 - cell.com
The localization of mRNAs to subcellular compartments provides a mechanism for
regulating gene expression with exquisite temporal and spatial control. Recent studies …

Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB

P Rajasethupathy, F Fiumara, R Sheridan, D Betel… - Neuron, 2009 - cell.com
Memory storage and memory-related synaptic plasticity rely on precise spatiotemporal
regulation of gene expression. To explore the role of small regulatory RNAs in learning …

Demyelination causes synaptic alterations in hippocampi from multiple sclerosis patients

R Dutta, A Chang, MK Doud, GJ Kidd… - Annals of …, 2011 - Wiley Online Library
Abstract Objective: Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the
human central nervous system. Although the clinical impact of gray matter pathology in MS …

Mechanisms of dendritic mRNA transport and its role in synaptic tagging

M Doyle, MA Kiebler - The EMBO journal, 2011 - embopress.org
The localization of RNAs critically contributes to many important cellular processes in an
organism, such as the establishment of polarity, asymmetric division and migration during …

[HTML][HTML] Synapse formation: from cellular and molecular mechanisms to neurodevelopmental and neurodegenerative disorders

S Batool, H Raza, J Zaidi, S Riaz… - Journal of …, 2019 - journals.physiology.org
The precise patterns of neuronal assembly during development determine all functional
outputs of a nervous system; these may range from simple reflexes to learning, memory …

Rapid active zone remodeling consolidates presynaptic potentiation

MA Böhme, AW McCarthy, AT Grasskamp… - Nature …, 2019 - nature.com
Neuronal communication across synapses relies on neurotransmitter release from
presynaptic active zones (AZs) followed by postsynaptic transmitter detection. Synaptic …

[HTML][HTML] Neuralized1 activates CPEB3: a function for nonproteolytic ubiquitin in synaptic plasticity and memory storage

E Pavlopoulos, P Trifilieff, V Chevaleyre, L Fioriti… - Cell, 2011 - cell.com
The cytoplasmic polyadenylation element-binding protein 3 (CPEB3), a regulator of local
protein synthesis, is the mouse homolog of ApCPEB, a functional prion protein in Aplysia …

How serotonin receptors regulate morphogenic signalling in neurons

A Wirth, K Holst, E Ponimaskin - Progress in neurobiology, 2017 - Elsevier
Abstract Serotonin (5-hydroxytrympamine or 5-HT) is one of the phylogenetically oldest
neurotransmitters, and the serotonergic system is among the earliest developed neuronal …