The roles of zinc finger proteins in colorectal cancer

AS Iyer, MR Shaik, JP Raufman, G Xie - International journal of molecular …, 2023 - mdpi.com
Despite colorectal cancer remaining a leading worldwide cause of cancer-related death,
there remains a paucity of effective treatments for advanced disease. The molecular …

Role of DNA Methyltransferases (DNMTs) in metastasis

MZ Qureshi, UY Sabitaliyevich… - Cellular and …, 2022 - mail.cellmolbiol.org
The DNA methyltransferase (DNMT) family constitutes a conserved set of DNA-modifying
enzymes which have essential functions in the modulation of epigenetics. The fundamental …

Systematic exo-endo encapsulation of hydroxyurea (HU) by Cu, Ag, and Au-doped gallium nitride nanotubes (GaNNT) for smart therapeutic delivery

H Louis, EN Mbim, GA Okon, UO Edet… - Computers in Biology …, 2023 - Elsevier
Similar to the more well-known carbon nanotubes, gallium nitride nanotubes (GaNNT) are
among the materials that scientists have found to be extremely helpful in transporting drugs …

[HTML][HTML] Induction of Invasive Basal Phenotype in Triple-Negative Breast Cancers by Long Noncoding RNA BORG

F Niazi, KA Parker, SJ Mason, S Singh, WP Schiemann… - Cancers, 2024 - mdpi.com
Simple Summary Breast cancer remains a major health issue in the United States and
around the world. While progress has been made in curing most types of breast cancer …

AKT inhibition sensitizes EVI1 expressing colon cancer cells to irinotecan therapy by regulating the Akt/mTOR axis

Pradeepa, V Suresh, S Senapati, S Chakraborty - Cellular Oncology, 2022 - Springer
Purpose Ecotropic viral integration site 1 (EVI1) is an oncogenic transcription factor that has
been attributed to chemotherapy resistance in different cancers. As yet, however, its role in …

MECOM: a bioinformatics and experimentally identified marker for the diagnosis and prognosis of lung adenocarcinoma

A Li, M Li, J Wang, J Zhou, T Yang, M Fan… - Biomarkers in …, 2024 - Taylor & Francis
Objective: We aimed to explore the clinical value of MDS1 and EVI1 complex locus
(MECOM) in lung adenocarcinoma (LUAD). Methods: Bioinformatics and experimental …

Silencing effects of mutant RAS signalling on transcriptomes

C Sers, R Schäfer - Advances in Biological Regulation, 2023 - Elsevier
Mutated genes of the RAS family encoding small GTP-binding proteins drive numerous
cancers, including pancreatic, colon and lung tumors. Besides the numerous effects of …