Piano stool Ru (II)-arene complexes having three monodentate legs: A comprehensive review on their development as anticancer therapeutics over the past decade

S Swaminathan, J Haribabu, N Balakrishnan… - Coordination chemistry …, 2022 - Elsevier
The popularity of RAPTA-C in in vivo studies has steered the way for complexes of the type
[Ru (η 6-arene)(X)(Y)(Z)] n+ (where X, Y and Z are monodentate ligands) to be developed …

Monodentately-coordinated bioactive moieties in multimodal half-sandwich organoruthenium anticancer agents

TR Steel, F Walsh, A Wieczorek-Błauż, M Hanif… - Coordination chemistry …, 2021 - Elsevier
Metallodrugs have a central role in the treatment and diagnosis of diseases. To overcome
potential toxicity and equip metal-based anticancer agents with biological activity, the choice …

Impact of aliphatic acyl and aromatic thioamide substituents on the anticancer activity of Ru (ii)-p-cymene complexes with acylthiourea ligands—in vitro and in vivo …

S Swaminathan, J Haribabu, MKM Subarkhan… - Dalton …, 2021 - pubs.rsc.org
Six different acylthiourea ligands (L1–L6) and their corresponding Ru (II)-p-cymene
complexes (P1–P6) were designed to explore the structure–activity relationship of the …

Synthesis of palladium (II) complexes via Michael addition: antiproliferative effects through ROS-mediated mitochondrial apoptosis and docking with SARS-CoV-2

J Haribabu, S Srividya, D Mahendiran… - Inorganic …, 2020 - ACS Publications
Metal complexes have numerous applications in the current era, particularly in the field of
pharmaceutical chemistry and catalysis. A novel synthetic approach for the same is always a …

New organoruthenium (II) complexes containing N, X-donor (X= O, S) heterocyclic chelators: synthesis, spectral characterization, in vitro cytotoxicity and apoptosis …

G Kalaiarasi, MM Subarkhan, CKF Safwana… - Inorganica chimica …, 2022 - Elsevier
Four Schiff base ligands namely ((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene)
semicarbazide)(HL 1),((1E)-1-(1-(6-chloro-2-oxo-2H-chromen-3-yl) ethylidene …

Coordination behavior of acylthiourea ligands in their Ru (II)–benzene complexes─ structures and anticancer activity

S Swaminathan, J Haribabu… - …, 2022 - ACS Publications
Acylthiourea ligands have applications in both synthetic and applied chemistry. The skeleton
of the ligand contains several heteroatoms which offer variable coordination modes in their …

An overview on the anticancer activity of Ru (II)/acylthiourea complexes

GH Ribeiro, AR Costa, AR de Souza… - Coordination Chemistry …, 2023 - Elsevier
This review outlines research on the development of ruthenium complexes containing
acylthiourea ligands with potential antitumor activity, which have been leveraged in recent …

Hinged Bipodal Furoylthiourea-Based Ru(II)-Arene Complexes: Effect of (ortho, meta, or para)-Substitution on Coordination and Anticancer Activity

S Swaminathan, J Haribabu, M Dharmasivam… - Inorganic …, 2023 - ACS Publications
We set out to design and synthesize bipodal ligands with the phenyl group as the spacer
and varied the substitution on the spacer between ortho (L1), meta (L2), and para (L3). The …

[HTML][HTML] Effect of morphology and (Sn, Cr) doping on in vitro antiproliferation properties of hydrothermally synthesized 1D GaOOH nanostructures

R Pilliadugula, J Haribabu, MKM Subarkhan… - Journal of science …, 2021 - Elsevier
GaOOH powders of submicron dimensions were synthesized through a simple, surfactant-
free hydrothermal synthesis at pH values of 7 and 14. Sn and Cr at concentrations of 2 mol …

Multi-Biofunctional Properties of Phytofabricated Selenium Nanoparticles From Carica papaya Fruit Extract: Antioxidant, Antimicrobial, Antimycotoxin, Anticancer, and …

SR Vundela, NK Kalagatur, A Nagaraj… - Frontiers in …, 2022 - frontiersin.org
The present study focused on phytofabrication of selenium nanoparticles (SeNPs) from
Carica papaya extract and exploration of their multi-biofunctional features. Total phenolics …