Galectin-3 is a β-galactoside-binding lectin which is important in numerous biological
activities in various organs, including cell proliferation, apoptotic regulation, inflammation …

Alzheimer's disease (AD) is the most common cause of dementia and is characterized by the
deposition of extracellular aggregates of amyloid-β (Aβ), the formation of intraneuronal tau …

Macrophages are essential for skeletal muscle homeostasis, but how their dysregulation
contributes to the development of fibrosis in muscle disease remains unclear. Here, we used …

Sciatic nerve crush injury triggers sterile inflammation within the distal nerve and axotomized
dorsal root ganglia (DRGs). Granulocytes and pro-inflammatory Ly6Chigh monocytes …

Microglia were considered as immune cells in inflammation until their angiogenic role was
widely understood. Although the pro-inflammatory role of microglia in retinal angiogenesis …

Aging is a significant risk factor associated with the progression of CNS neurodegenerative
diseases including multiple sclerosis (MS). Microglia, the resident macrophages of the CNS …

The galectin family consists of carbohydrate (glycan) binding proteins that are expressed by
a wide variety of cells and bind to galactose-containing glycans. Galectins can be located in …

Background Excess polymorphonuclear neutrophil (PMN) recruitment or excessive
neutrophil extracellular trap (NET) formation can lead to the development of multiple organ …

Aims The alternatively activated macrophages have shown a cardioprotective effect in heart
failure. However, the effect of M2 adoptive transfer in non-ischemic heart failure is unknown …

The involvement of the central nervous system (CNS) during human acute and chronic
Chagas disease (CD) has been largely reported. Meningoencephalitis is a frequent finding …