Human mesenchymal stem cells-current trends and future prospective

I Ullah, RB Subbarao, GJ Rho - Bioscience reports, 2015 - portlandpress.com
Stem cells are cells specialized cell, capable of renewing themselves through cell division
and can differentiate into multi-lineage cells. These cells are categorized as embryonic stem …

Concise review: mesenchymal stem cells in neurodegenerative diseases

R Volkman, D Offen - Stem cells, 2017 - academic.oup.com
Stem cell-based therapies for neurodegenerative diseases aim at halting clinical
deterioration by regeneration and by providing local support for damaged tissue …

Pluripotent stem cell-based therapy for Parkinson's disease: Current status and future prospects

KC Sonntag, B Song, N Lee, JH Jung, Y Cha… - Progress in …, 2018 - Elsevier
Parkinson's disease (PD) is one of the most common neurodegenerative disorders, which
affects about 0.3% of the general population. As the population in the developed world ages …

Conversion of human bone marrow-derived mesenchymal stem cells into tendon progenitor cells by ectopic expression of scleraxis

P Alberton, C Popov, M Prägert, J Kohler… - Stem cells and …, 2012 - liebertpub.com
Tendons and ligaments (T/L) are dense connective tissues of mesodermal origin. During
embryonic development, the tendon-specific cells descend from a sub-set of mesenchymal …

Clinical applications of mesenchymal stem cells in chronic diseases

A Farini, C Sitzia, S Erratico, M Meregalli… - Stem cells …, 2014 - Wiley Online Library
Extraordinary progress in understanding several key features of stem cells has been made
in the last ten years, including definition of the niche, and identification of signals regulating …

Mesenchymal stem cells and neuroregeneration in Parkinson's disease

A Glavaski-Joksimovic, MC Bohn - Experimental neurology, 2013 - Elsevier
Parkinson's disease (PD) is a prevalent neurodegenerative disorder characterized by a
progressive and extensive loss of dopaminergic (DA) neurons in the substantia nigra pars …

Protective effects of neurotrophic factor–secreting cells in a 6-OHDA rat model of Parkinson disease

O Sadan, M Bahat-Stromza, Y Barhum… - Stem cells and …, 2009 - liebertpub.com
Stem cell-based therapy is a promising treatment for neurodegenerative diseases. In our
laboratory, a novel protocol has been developed to induce bone marrow-derived …

Introducing transcription factors to multipotent mesenchymal stem cells: making transdifferentiation possible

R Barzilay, E Melamed, D Offen - Stem cells, 2009 - academic.oup.com
Multipotent mesenchymal stem cells (MSCs) represent a promising autologous source for
regenerative medicine. Because MSCs can be isolated from adult tissues, they represent an …

Effects of fine particulate matter on bone marrow-conserved hematopoietic and mesenchymal stem cells: a systematic review

G Bhattarai, SK Shrestha, HJ Sim, JC Lee… - … & Molecular Medicine, 2024 - nature.com
The harmful effects of fine particulate matter≤ 2.5 µm in size (PM2. 5) on human health have
received considerable attention. However, while the impact of PM2. 5 on the respiratory and …

Bone-marrow-derived mesenchymal stem cell therapy for neurodegenerative diseases

O Sadan, E Melamed, D Offen - Expert opinion on biological …, 2009 - Taylor & Francis
Background: Stem-cell-based therapy is a promising new approach to handling
neurodegenerative diseases. One of the most promising cellular sources is bone-marrow …