Importance of fluorine in benzazole compounds

T Al-Harthy, W Zoghaib, R Abdel-Jalil - Molecules, 2020 - mdpi.com
Fluorine-containing heterocycles continue to receive considerable attention due to their
unique properties. In medicinal chemistry, the incorporation of fluorine in small molecules …

α-Aminoazoles/azines: key reaction partners for multicomponent reactions

S Imtiaz, S Banoo - RSC advances, 2021 - pubs.rsc.org
Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration
by researchers owing to their key role in diverse biological and physiological processes. The …

Benzothiazole: A versatile and multitargeted pharmacophore in the field of medicinal chemistry

S Agarwal, D Gandhi, P Kalal - Letters in Organic Chemistry, 2017 - ingentaconnect.com
Background: Heterocycles are the gold mines in medicinal chemistry. Most drugs used in
today's medicinal period possess a heterocyclic nucleus. One of the interesting …

Synthetic strategies for fused benzothiazoles: past, present, and future

MN Bhoi, MA Borad, HD Patel - Synthetic Communications, 2014 - Taylor & Francis
Benzothiazole is used as a building block in organic synthesis, which serves as a key
template for the development of various therapeutic agents and shows a wide spectrum of …

The trimethoxyphenyl (TMP) functional group: a versatile pharmacophore

MA Langarizadeh, A Ameri, MR Tavakoli… - Medicinal Chemistry …, 2023 - Springer
The Trimethoxyphenyl (TMP) group serves as a pharmacophore in numerous potent agents
exhibiting diverse bioactivity effects. This moiety is prominently present in the molecular …

Insight View on Synthetic Strategies and Biological Applications of Pyrimidobenzothiazoles

DK Agarwal, N Sahiba, A Sethiya, J Soni… - Mini-Reviews in …, 2021 - ingentaconnect.com
Pyrimidobenzothiazoles and its derivatives are important structural scaffolds in the field of
synthetic organic chemistry and medicinal chemistry. The review is focused on one pot …

Nano-Fe3O4@SiO2–TiCl3 as a novel nano-magnetic catalyst for the synthesis of 4H-pyrimido[2,1-b]benzothiazoles

SA Fazeli-Attar, BBF Mirjalili - Research on Chemical Intermediates, 2018 - Springer
Abstract Fe 3 O 4@ SiO 2–TiCl 3 NPs, a novel core shell catalyst, was synthesized via
preparing Fe 3 O 4@ SiO 2 as a magnetic support followed by treatment with titanium …

Nano-Co-[4-chlorophenyl-salicylaldimine-pyranopyrimidine dione] Cl 2 as a new Schiff base complex and catalyst for the one-pot synthesis of some 4 H-pyrimido [2, 1 …

AR Moosavi-Zare, H Goudarziafshar… - Research on Chemical …, 2020 - Springer
Abstract Nano-Co-[4-clolorophenyl-salsylaldimine-pyranopyrimidine dione] Cl 2 {Nano-[Co-
4CSP] Cl 2} was prepared and fully characterized as a new nano-Schiff base complex. Nano …

Microwave assisted synthesis of biorelevant benzazoles

K Seth, P Purohit, AK Chakraborti - Current Medicinal Chemistry, 2017 - ingentaconnect.com
The benzazole scaffolds are present in various therapeutic agents and have been
recognized as the essential pharmacophore for diverse biological activities. These have …

Fe3O4@nano-dextrin–OPO3H2: a bio-based magnetic nano-catalyst for the synthesis of 4H-pyrimido[2,1-b]benzothiazole derivatives

A Dehghani Tafti, BBF Mirjalili, N Salehi… - Journal of the Iranian …, 2022 - Springer
Abstract Fe3O4@ nano-dextrin–OPO3H2 as a bio-based nano-catalyst was successfully
synthesized via preparation of Fe3O4@ nano-dextrin as a magnetic core–shell structure …