Neural stem cell therapy for subacute and chronic ischemic stroke

AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …

Neural stem cells therapy for ischemic stroke: progress and challenges

T Zhao, T Zhu, L Xie, Y Li, R Xie, F Xu, H Tang… - Translational stroke …, 2022 - Springer
Ischemic stroke, with its high morbidity and mortality, is the most common cerebrovascular
accident and results in severe neurological deficits. Despite advances in medical and …

Neural stem cells transfected with reactive oxygen species–responsive polyplexes for effective treatment of ischemic stroke

XC Jiang, JJ Xiang, HH Wu, TY Zhang… - Advanced …, 2019 - Wiley Online Library
Neural stem cells (NSCs), capable of ischemia‐homing, regeneration, and differentiation,
exert strong therapeutic potentials in treating ischemic stroke, but the curative effect is limited …

[HTML][HTML] Immunomodulation: The next target of mesenchymal stem cell-derived exosomes in the context of ischemic stroke

XQ Shan, YY Luo, J Chang, JJ Song… - World journal of stem …, 2023 - ncbi.nlm.nih.gov
Ischemic stroke (IS) is the most prevalent form of brain disease, characterized by high
morbidity, disability, and mortality. However, there is still a lack of ideal prevention and …

Therapeutic potential of stem cells for treatment of neurodegenerative diseases

H Ahmadian-Moghadam, MS Sadat-Shirazi… - Biotechnology …, 2020 - Springer
Neurodegenerative diseases are caused by a loss of neurons within the peripheral or
central nervous system. Inadequate repairability in the central nervous system and failure of …

Mechanism of miR-320 in regulating biological characteristics of ischemic cerebral neuron by mediating Nox2/ROS pathway

W Shen, Y Lu, J Hu, H Le, W Yu, W Xu, W Yu… - Journal of Molecular …, 2020 - Springer
This study aimed to explore the mechanism of miR-320 in regulating biological
characteristics of ischemic cerebral neuron by mediating Nox2/ROS pathway. Primary …

Preconditioned neurons with NaB and nicorandil, a favorable source for stroke cell therapy

SM Hosseini, SM Ziaee, KH Haider… - Journal of Cellular …, 2018 - Wiley Online Library
Poor survival of stem cells in the harsh microenvironment at the site of stroke, especially
during acute phase of injury, remains a serious obstacle to achieve the desired prognosis …

放散式冲击波通过Notch1/Hes1 通路调节脑缺血后海马组织中神经干细胞的增殖与分化

苏明珠, 马跃文 - 中国组织工程研究, 2021 - cjter.com
放散式冲击波通过Notch1/Hes1通路调节脑缺血后海马组织中神经干细胞的增殖与分化 中国
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Preclinical studies on neural stem/progenitor cell therapy for ischemic stroke: a systematic review

M Zhang, K Wang, C Xue, C Xie, Z Wang… - Current Stem Cell …, 2023 - ingentaconnect.com
Background: Neural stem/progenitor cells (NSPCs) transplantation has been recognized in
recent years as an effective strategy for the treatment of ischemic stroke. Several preclinical …

Routes and methods of neural stem cells injection in cerebral ischemia

XY Yang, X Zhang, JF Cao, M Wu, SY Chen, L Chen - Ibrain, 2023 - Wiley Online Library
Cerebral ischemia is a serious cerebrovascular disease with the characteristics of high
morbidity, disability, and mortality. Currently, stem cell therapy has been extensively applied …