A frameshift in Yersinia pestis rcsD alters canonical Rcs signalling to preserve flea-mammal plague transmission cycles

XP Guo, HQ Yan, W Yang, Z Yin, V Vadyvaloo, D Zhou… - Elife, 2023 - elifesciences.org
Multiple genetic changes in the enteric pathogen Yersinia pseudotuberculosis have driven
the emergence of Yesinia pestis, the arthropod-borne, etiological agent of plague. These …

The yeasts phosphorelay systems: a comparative view

G Salas-Delgado, L Ongay-Larios… - World Journal of …, 2017 - Springer
Cells contain signal transduction pathways that mediate communication between the
extracellular environment and the cell interior. These pathways control transcriptional …

Multistep phosphorelay in fungi: The enigma of multiple signals and a limited number of signaling pathways

S Jacob, E Thines - Mycological Progress, 2017 - Springer
Current knowledge of fungal ecology depends on the understanding of the perception and
processing of biotic and abiotic factors facilitating environmental interactions. Ongoing …

Structural and functional insights underlying recognition of histidine phosphotransfer protein in fungal phosphorelay systems

F Paredes-Martínez, L Eixerés… - Communications …, 2024 - nature.com
In human pathogenic fungi, receiver domains from hybrid histidine kinases (hHK) have to
recognize one HPt. To understand the recognition mechanism, we have assessed …

Genetic Analysis Reveals a Requirement for the Hybrid Sensor Kinase RscS in para-Aminobenzoic Acid/Calcium-Induced Biofilm Formation by Vibrio fischeri

CN Dial, BL Fung, KL Visick - Journal of Bacteriology, 2023 - Am Soc Microbiol
The marine bacterium Vibrio fischeri initiates symbiotic colonization of its squid host,
Euprymna scolopes, by forming and dispersing from a biofilm dependent on the sy mbiosis p …

A radical reimagining of fungal two-component regulatory systems

RB Bourret, EN Kennedy, CA Foster, VE Sepúlveda… - Trends in …, 2021 - cell.com
Bacterial two-component regulatory systems (TCSs) mediate signal transduction by
transferring phosphoryl groups between sensor kinase and response regulator proteins …

Predicted Functional and Structural Diversity of Receiver Domains in Fungal Two-Component Regulatory Systems

RB Bourret, CA Foster, WE Goldman - Msphere, 2021 - Am Soc Microbiol
Fungal two-component regulatory systems incorporate receiver domains into hybrid
histidine kinases (HHKs) and response regulators. We constructed a nonredundant …

The phosphorelay signal transduction system in Candida glabrata: an in silico analysis

N Carapia-Minero, JA Castelán-Vega… - Journal of Molecular …, 2018 - Springer
Signaling systems allow microorganisms to sense and respond to different stimuli through
the modification of gene expression. The phosphorelay signal transduction system in …

A frameshift in Yersinia pestis rcsD leads to expression of a small HPt variant that alters canonical Rcs signalling to preserve flea-mammal plague transmission cycles

XP Guo, HQ Yan, W Yang, Z Yin, V Vadyvaloo, D Zhou… - bioRxiv, 2022 - biorxiv.org
Multiple genetic changes in the enteric pathogen Yersinia pseudotuberculosis have driven
the emergence of Yesinia pestis, the arthropod-borne, etiological agent of plague. These …

[引用][C] Role of surfactant protein D on in vivo alveolar macrophage phagocytosis of Cryptococcus neoformans by the regulation of p38 MAPK pathway activation. Pulm …

O Abdel-Razek, X Liu, S Javidiparsijani, G Wang