The historic term 'histiocytosis' meaning 'tissue cell'is used as a unifying concept for
diseases characterized by pathogenic myeloid cells that share histological features with …

Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors
that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …

Histiocytic neoplasms are clonal, hematopoietic disorders characterized by an accumulation
of abnormal, monocyte-derived dendritic cells or macrophages in Langerhans cell …

Granulomatous inflammation is a histologic pattern of tissue reaction which appears
following cell injury. Granulomatous inflammation is caused by a variety of conditions …

Langerhans cell histiocytosis (LCH) is a myeloproliferative disorder characterized by lesions
composed of pathological CD207+ dendritic cells with an inflammatory infiltrate …

Langerhans-Cell Histiocytosis A spectrum of diseases formerly known as histiocytosis X and
now called Langerhans-cell histiocytosis is characterized by ERK pathway activation …

Langerhans cell histiocytosis (LCH) is a clonal disorder with elusive etiology, characterized
by the accumulation of CD207+ dendritic cells (DCs) in inflammatory lesions. Recurrent …

Langerhans cell histiocytosis (LCH)-III tested risk-adjusted, intensified, longer treatment of
multisystem LCH (MS-LCH), for which optimal therapy has been elusive. Stratified by risk …

Langerhans cell histiocytosis (LCH) is a rare systemic disorder characterized by the
accumulation of CD 1a+/Langerin+ LCH cells and wide‐ranging organ involvement …

Abstract “Langerhans cell histiocytosis”(LCH) describes a spectrum of clinical presentations
ranging from a single bone lesion or trivial skin rash to an explosive disseminated disease …