The COVID-19 pandemic now totaling 13,000,000 cases and over 571,000 deaths has
continued to teach the medical, scientific and lay communities about viral infectious disease …

The endothelial glycocalyx is a gel-like layer on the luminal side of blood vessels that is
composed of glycosaminoglycans and the proteins that tether them to the plasma …

In atherosclerosis patients, vascular endothelial dysfunction is commonly observed
alongside damage of the vascular endothelial glycocalyx, an extracellular matrix bound to …

The glycocalyx is a layer coating the luminal surface of vascular endothelial cells. It is vital
for endothelial function as it participates in microvascular reactivity, endothelium interaction …

Abstracts Background The number of studies measuring breakdown products of the
glycocalyx in plasma has increased rapidly during the past decade. The purpose of the …

Hemorrhagic shock (HS) management is based on a timely, rapid, definitive source control
of bleeding/s and on blood loss replacement. Stopping the hemorrhage from progressing …

There is no standard definition for trauma-induced coagulopathy (TIC). However, it could be
defined as an abnormal hemostatic response secondary to trauma. The terms “early TIC” …

Both heparanase and syndecan-1 are known to be present and active in disease
pathobiology. An important feature of syndecan-1 related to its role in pathologies is that it …

Disseminated intravascular coagulation can occur due to different causes but commonly
following sepsis. Trauma-induced coagulopathy (TIC) occurs on hospital arrival in …

Objective: The endothelial glycocalyx (eGC) is a dynamic and multicomponent layer of
macromolecules found at the surface of vascular endothelium, which is largely …