[HTML][HTML] Functional amyloid and other protein fibers in the biofilm matrix

E Erskine, CE MacPhee, NR Stanley-Wall - Journal of Molecular Biology, 2018 - Elsevier
Biofilms are ubiquitous in the natural and man-made environment. They are defined as
microbes that are encapsulated in an extracellular, self-produced, biofilm matrix. Growing …

The Biology of Streptococcus mutans

JA Lemos, SR Palmer, L Zeng, ZT Wen… - Microbiology …, 2019 - Am Soc Microbiol
As a major etiological agent of human dental caries, Streptococcus mutans resides primarily
in biofilms that form on the tooth surfaces, also known as dental plaque. In addition to caries …

Genetics, structure, and function of group A streptococcal pili

M Nakata, B Kreikemeyer - Frontiers in Microbiology, 2021 - frontiersin.org
Streptococcus pyogenes (Group A Streptococcus; GAS) is an exclusively human pathogen.
This bacterial species is responsible for a large variety of infections, ranging from purulent …

Functional amyloid formation by Streptococcus mutans

MW Oli, HN Otoo, PJ Crowley, KP Heim… - …, 2012 - microbiologyresearch.org
Dental caries is a common infectious disease associated with acidogenic and aciduric
bacteria, including Streptococcus mutans. Organisms that cause cavities form recalcitrant …

Functional amyloids in Streptococcus mutans, their use as targets of biofilm inhibition and initial characterization of SMU_63c

RN Besingi, IB Wenderska, DB Senadheera… - …, 2017 - microbiologyresearch.org
Amyloids have been identified as functional components of the extracellular matrix of
bacterial biofilms. Streptococcus mutans is an established aetiologic agent of dental caries …

Inhibition of Major Virulence Pathways of Streptococcus mutans by Quercitrin and Deoxynojirimycin: A Synergistic Approach of Infection Control

S Hasan, K Singh, M Danisuddin, PK Verma… - PLoS one, 2014 - journals.plos.org
Objectives To evaluate the synergistic effect of Quercitrin and Deoxynojirimycin (DNJ)
together with their individual inhibitory effect against virulence pathways of Streptococcus …

Structure and assembly of Gram-positive bacterial pili: unique covalent polymers

HJ Kang, EN Baker - Current opinion in structural biology, 2012 - Elsevier
Bacterial pili are long, multi-subunit protein assemblies that extend from bacterial surfaces,
mediating adhesion and colonisation. The recently characterised pili expressed by Gram …

Binding Forces of Streptococcus mutans P1 Adhesin

RMA Sullan, JK Li, PJ Crowley, LJ Brady, YF Dufrêne - ACS nano, 2015 - ACS Publications
Streptococcus mutans is a Gram-positive oral bacterium that is a primary etiological agent
associated with human dental caries. In the oral cavity, S. mutans adheres to immobilized …

Streptococcus mutans Displays Altered Stress Responses While Enhancing Biofilm Formation by Lactobacillus casei in Mixed-Species Consortium

ZT Wen, S Liao, JP Bitoun, A De… - Frontiers in cellular …, 2017 - frontiersin.org
Like Streptococcus mutans, lactobacilli are commonly isolated from carious sites, although
their exact role in caries development remains unclear. This study used mixed-species …

Enhanced purification coupled with biophysical analyses shows cross-β structure as a core building block for Streptococcus mutans functional amyloids

AL Barran-Berdon, S Ocampo, M Haider… - Scientific Reports, 2020 - nature.com
Streptococcus mutans is an etiologic agent of human dental caries that forms dental plaque
biofilms containing functional amyloids. Three amyloidogenic proteins, P1, WapA, and …