Pathogenic variants in genes that cause dilated cardiomyopathy (DCM) and arrhythmogenic
cardiomyopathy (ACM) convey high risks for the development of heart failure through …

The SLIT family (SLIT1-3) of highly conserved glycoproteins was originally identified as
ligands for the Roundabout (ROBO) family of single-pass transmembrane receptors, serving …

SLIT ligand and its receptor ROBO were initially recognized for their role in axon guidance in
central nervous system development. In recent years, as research has advanced, the role of …

Background Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs) have
garnered considerable attention as prospective modalities of treatment for liver fibrosis (LF) …

Background Cardiac fibroblast activation protein (FAP) has an emerging role in heart failure
(HF). A paradoxical reduction in its levels in pathological conditions associated with acute …

Aim: The Shexiang Baoxin Pill (SBP) has been extensively used to treat cardiovascular
diseases in China for four decades, and its clinical efficacy has been widely approved …

Background Cardiac fibrosis stiffens the ventricular wall, predisposes to cardiac arrhythmias
and contributes to the development of heart failure. In the present study, our aim was to …

To investigate single nucleotide polymorphism (SNP) loci associated with yearling wool
traits of fine-wool sheep for optimizing marker-assisted selection and dissection of the …

Choroidal neovascularization (CNV) is a hallmark of neovascular age-related macular
degeneration (nAMD) and a major contributor to vision loss in nAMD cases. However, the …

Long-haired individuals in the Tianzhu white yak population are a unique genetic resource,
and have important landscape value. Copy number variation (CNV) is an important source …