Pseudomonas aeruginosa: pathogenesis, virulence factors, antibiotic resistance, interaction with host, technology advances and emerging therapeutics

S Qin, W Xiao, C Zhou, Q Pu, X Deng, L Lan… - Signal transduction and …, 2022 - nature.com
Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that
infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive …

Relationship between quorum sensing and secretion systems

RT Pena, L Blasco, A Ambroa… - Frontiers in …, 2019 - frontiersin.org
Quorum sensing (QS) is a communication mechanism between bacteria that allows specific
processes to be controlled, such as biofilm formation, virulence factor expression, production …

Exploiting extracellular polymeric substances (EPS) controlling strategies for performance enhancement of biological wastewater treatments: an overview

Y Shi, J Huang, G Zeng, Y Gu, Y Chen, Y Hu, B Tang… - Chemosphere, 2017 - Elsevier
Extracellular polymeric substances (EPS) are present both outside of the cells and in the
interior of microbial aggregates, and account for a main component in microbial aggregates …

Structures of gram-negative cell walls and their derived membrane vesicles

TJ Beveridge - Journal of bacteriology, 1999 - Am Soc Microbiol
Gram-negative cell walls are strong enough to withstand 3 atm of turgor pressure (40), tough
enough to endure extreme temperatures and pHs (eg, Thiobacillus ferrooxidans grows at a …

Type IV pilin proteins: versatile molecular modules

CL Giltner, Y Nguyen, LL Burrows - Microbiology and molecular …, 2012 - Am Soc Microbiol
SUMMARY Type IV pili (T4P) are multifunctional protein fibers produced on the surfaces of a
wide variety of bacteria and archaea. The major subunit of T4P is the type IV pilin, and …

Bacterial biocatalysts: molecular biology, three-dimensional structures, and biotechnological applications of lipases

KE Jaeger, BW Dijkstra, MT Reetz - Annual Reviews in …, 1999 - annualreviews.org
▪ Abstract Bacteria produce and secrete lipases, which can catalyze both the hydrolysis and
the synthesis of long-chain acylglycerols. These reactions usually proceed with high …

A hierarchical cascade of second messengers regulates Pseudomonas aeruginosa surface behaviors

Y Luo, K Zhao, AE Baker, SL Kuchma, KA Coggan… - MBio, 2015 - Am Soc Microbiol
Biofilms are surface-attached multicellular communities. Using single-cell tracking
microscopy, we showed that a pilY1 mutant of Pseudomonas aeruginosa is defective in …

Type II secretion and pathogenesis

M Sandkvist - Infection and immunity, 2001 - Am Soc Microbiol
Extracellular secretion of proteins is regarded as a major virulence mechanism in bacterial
infection. Proteins destined for the extracellular environment of gram-negative bacteria have …

Type II protein secretion and its relationship to bacterial type IV pili and archaeal flagella

CR Peabody, YJ Chung, MR Yen… - …, 2003 - microbiologyresearch.org
Homologues of the protein constituents of the Klebsiella pneumoniae (Klebsiella oxytoca)
type II secreton (T2S), the Pseudomonas aeruginosa type IV pilus/fimbrium biogenesis …

Biology of type II secretion

M Sandkvist - Molecular microbiology, 2001 - Wiley Online Library
The type II secretion pathway or the main terminal branch of the general secretion pathway,
as it has also been referred to, is widely distributed among Proteobacteria, in which it is …